253 Heart Failure Mgt

Question 1

ALDO-HF: improved echocardiographic indices of diastolic dysfunction when given this drug

Answer 1

Spironolactone

Question 2

TOPCAT: improvement of primary composite endpoint in heart failure but can lead to hyperkalemia

Answer 2

Aldosterone antagonist

Question 3

Beta blockers tested and proven to improve survival in heart failure

Answer 3

Carvedilol
Bisoprolol
Metropolis succinate

Question 4

Reversible heart failure has been described as consequence of what micronutrient deficiency

Answer 4

Thiamine and selenium

Question 5

A 61M presents with 5 days fatigue. shortness of breath, orthopnea and PND. PE BP 120/80 mmHg, CR 112 bpm, RR 26 cpm. Distended neck veins, fine crackles bilateral, apex beat at the 6th ICS left anterior axillary line. (+) S3 and grade 2 bipedal edema. 2Decho shows EF of 25%. Which drug must be avoided due to its negative inotropic effect?
A. Diltiazem
B. Lisinopril
C. Spironolactone
D. Carvedilol

Answer 5

A. Diltiazem

Question 6

Therapeutic targets in HFpEF

Answer 6

control of congestion, stabilisation of heart rate and blood pressure, and efforts at improving exercise
tolerance

Question 7

NEAT-HFpEF

Answer 7

Nitrates

Question 8

Form the cornerstone of pharmacotherapy and lead to attenuation of decline and improvement in cardiac structure and function in heart failure

Answer 8

RAAS blockers and beta blockers

Question 9

Antiarrhythmic drug therapy should be restricted to

Answer 9

amiodarone and dofetilide

Question 10

Heart failure patients who benefit from CRT or cardiac resynchronization therapy

Answer 10

QRS width of >149 ms and a left bundle branch block pattern.