Local anesthetics

Question 1

Local anesthetic

• Also an anti-arrhythmic
• IV use for local analgesia
  
  • Causes additional CNS depression and increased GI motility in horses
  • Interferes with glutamate action at NMDA receptors
  • Interferes with sodium potassium channels in spinal chord
  • Cats don’t metabolize as well as dogs–> greater cardiovascular effects

Answer 1

Lidocain

Question 2

Local anesthetic

• Slower onset, but long duration of action
  
  • Selectivity for sensory nerves
  • If over dose high enough to get cardiovascular effects, hard to save patients

Answer 2

Bupivicain

Question 3

Local anesthetic

• Long acting
• Less toxicity than Bupivicain

Answer 3

Ropivacain