322-A&P EXAM I Flashcards
Transrespiratory Pressure
- Sum of transpulmonary pressure (PL) and transthoracic pressure (PW)
- Inward and outward recoil forces of the lungs and thorax are in equilibrium with each other
- Is 0 mmHg under resting conditions
Ventilation
Process of moving gas in and out of lungs
Rule of thumb for estimating Anatomical Dead Space (Bedside method)
1 mL for every pound of ideal body weight
Structures in nose that increase surface area
Concha (turbinates)
Physiologic Dead Space
Sum of anatomical dead space and alveolar dead space
Normal value for total compliance in adult
0.1 L/cm H2O
Name the major muscles of inspiration
Diaphragm and External intercostal muscles
Functions of the upper airway
Warms, humidifies, and filters
Pharynx
Behind nasal-oral cavity—extends down to larynx
Narrowest part of airway in INFANT
Cricoid cartilage
Muscles used during forceful expiration
Internal intercostal muscles
Oropharynx
Behind oral cavity from soft palate to base of tongue
Explain how the chest wall increases in 3-dimensions
Combined rib and diaphragm movements during inspiration cause a 3-dimensional increase in thoracic volume: anterior-posterior, transverse, and vertical dimensions all increase simultaneously
Respiration
Process of moving oxygen and carbon dioxide between air in lungs and the blood
Hypoventilation
Alveolar ventilation momentarily removes less CO2 than the body produces, alveolar and blood PCO2 increases
Name the parts of the upper airway
Nose, oral cavity (mouth), pharynx (throat), and larynx (voice box)
Transthoracic Pressure (PW)
- Difference between intrapulmonary pressure (PPL) and body surface pressure (PBS)
- Pressure difference across thoracic wall
- Equal to outward recoil force of thorax when there is no airflow
Airway Resistance
Produced by frictional resistance to gas flow
Normal value of airway resistance in adult
0.5-1.5 cm H2O/L/sec
Correct units for Airway Resistance
cm H2O/L/sec
Normal value of Alveolar PCO2
40 mmHg
How does a patient with restrictive lung disease breathe?
Rapid and shallow
What is the pressure (in mmHg) of water vapor at normal body temperature?
47 mmHg
Name the two functions of surfactant in the lungs
- Decreases surface tension
2. Prevents alveolar collapse
Normal value of Alveolar PO2
100 mmHg
Nasopharynx
Behind nasal cavity down to soft palate
Bradypnea
Below normal rate of breathing
Normal value for lung compliance in adult
0.2 L/cm H2O
Anatomical Dead Space
Conducting airways from mouth to nose down to and including terminal bronchioles; no gas exchange occurs here
Describe LaPlace’s Law
- If collapsing force of surface tension is opposed by an equal counterpressure, alveolus remains distended
- Distending pressure (P) = 2 X Surface tension (T) / Alveolar radius (R)
Name major UNPAIRED cartilages of the larynx
- Epiglottic cartilage
- Thyroid cartilage
- Cricoid cartilage
What happens to chest wall/lung pleura and barometric pressure when a hole is present in chest wall?
a. The sub-atmospheric pressure within the cavity draws air in from atmosphere because of pressure gradient—leads to pneumothorax
Function of the diaphragm
Major muscle of ventilation, divides thoracic and abdominal cavities
Alveolar Dead Space
Volume contained in nonperfused alveoli (with no blood flow)
Volume changes in Obstructive lung diseases.
FVC–Decreased
FEV1-Normal
FEV1/FVC-Decreased
Name major PAIRED cartilages of the larynx
- Arytenoid cartliage
- Corniculate cartilage
- Cuneiform cartilage
What lung volume is being measured in Body Box?
Residual Volume
How is anatomical dead space measured?
Fowler technique, patient first exhales maximally to residual volume (RV), then takes maximal inhalation of 100% O2 to total lung capacity, then exhales to RV again
Name two characteristics of surfactant composition.
- Complex substance composed of 90% phospholipid and 10% protein
- Dipalmitoyl phosphatidylcholine (DPPC) comprises 50% of surfactant’s phospholipid content and is primarily responsible for surfactant’s surface-tension lowering properties
Narrowest part of airway in ADULT
Glottis
Conducting airways
Right/left main stem bronchi–>lobar bronchi–>segmental bronchi–>sub-segmental bronchi
Normal value for chest wall compliance in adult
0.2 L/cm H2O
Pulmonary Surfactant
Special surface-tension altering substance that lines the alveoli
Describe the conducting airways
- Tubes that connect atmospheric air with gas exchange membrane in lungs
- No gas exchange occurs in these airways
- Merely pathways through which air moves
Describe the respiratory mucosa epithelium
Pseudostratified, ciliated columnar epithelium interspersed with goblet cells
How does a patient with obstructive lung disease breathe?
Slow and deep
Tachypnea
Above normal rate of breathing
Hyperpnea
Above normal depth of breathing
What are the phrenic nerves and where do they originate?
- Supply motor innervation to hemidiaphragms
- Originate from right and left cervical nerve plexuses as branches of cervical spinal nerves C3 to C5
Where is pulmonary surfactant made?
It is secreted by alveolar type II cells
What muscles contract during inspiration?
Ventilatory muscles