5. Renal blood flow and glomerular filtration rate Flashcards

1
Q

three physical factors that contribute to GFR

A

hydraulic conductivity (permeability/porosity of the fenestrated endothelium) (Lp)
Surface area for filtration (Sf)
Capillary ultrafiltration pressure (PUF)

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2
Q

how do you get ultrafiltration coefficient (Kf)

A

hydraulic conductivities (Lp) x surface area for filtration (Sf)

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3
Q

GFR equation

A

GFR = Kf * PUF

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4
Q

PUF =

A

PGC-PBC-PiGC

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5
Q

what role do glomerular mesangial cells play regarding ultrafiltration coefficient

A

glomerular mesangial cells can contract and decrease surface area

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