Moraxella

Question 1

Moraxella bovis disease in bovines

Answer 1

Infectious bovine keratoconjunctivitis or ‘Pink eye’
Serous to purulent conjunctivitis and keratitis
Highly infectious

Question 2

Moraxella bovis Virulence Factors

Answer 2

Fimbriae - adhesion to host cell (eye), conjunctival and corneal epithelial cells
Capsule
LPS
Exotoxins - cytotoxin, pore forming toxin

Question 3

Moraxella bovis Pathogenesis

Answer 3

1. Speific attachment of bacteria to conjunctival/corneal epithelial
2. Production of toxin
   Destruction of tissue
3. Inflammation
4. Further growth and production of toxins
5. Increased susceptibility for other pathogens
6. Non infectious damage, dust
   Irreversible eye damage

Question 4

Moraxella bovis Predisposing Factors

Answer 4

Young cattle
Flies
Eye irritation (dust, sun)
Bovine herpesvirus 1

Question 5

Moraxella ovis

Answer 5

Associated with keratoconjunctivitis in bovines, sheep

Associated with pneumonia in bovines, sheep