Cephalosporins Flashcards

1
Q

Which agent is used in the treatment of childhood H. Influenza meningitis?

A
  1. Rocephin
  2. Claforan
    Both are 3RD gen Cephs
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2
Q

Which agent is used in Orthopedic surgery?

A

Ancef (1st gen)

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3
Q

How are the Cephalosporins excreted?

A

Via the kidney

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4
Q

T or F: There is less allergy sensitivity with Cephalosporins than with PCNs?

A

True

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5
Q

What are some adverse reactions to Cephalosporins?

A
  1. Bleeding (because they have an anti-Vitamin K effect)

2. Superinfections

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6
Q

What should you avoid taking with Cephs?

A

ETOH (Disulfiram like effect–makes you have a hangover as soon as you drink ETOH)

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7
Q

Why would you prescribe a 1st gen Ceph?

A
  1. They work as alternates to PCNS for Strep and pneumococcal inf
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8
Q

Why would you prescribe a 2nd gen Ceph?

A

They are the DOC for treatment of serious gram (-) infections:

  1. UTI
  2. Gram (-) bacteremia
  3. Pneumonia
  4. Mixed anaerobic/aerobic infection
  5. Inf. in febrile neutropenic its
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