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Yale Residency - Rabbits, Guinea Pigs, Misc. Rodents > 16. Viral, Chlamydial, and Fungal Diseases of GPs and Hamsters > Flashcards

16. Viral, Chlamydial, and Fungal Diseases of GPs and Hamsters Flashcards

(58 cards)

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1
Q

C/S of GPAdV (GP Adenovirus)

A

Subclinical infection, symptomatic when stressed

Pneumonia, sudden death

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2
Q

Pathology of GPAdV

A

Lung chnages - consolidation of lungs, necrotizing bronchiolitis, basophilic intranuclear inclusions

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3
Q

Prevention of GPAdV

A

Rederivation

Obtain GPs from stocks without history of GPAdV

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4
Q

Family of Caviid Herpes Virus 2 (GP Cytomegalovirus)

A

Herpesviridae

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5
Q

Subfamily of Caviid Herpes Virus 2 (GP Cytomegalovirus)

A

Betaherpesvirinae

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6
Q

C/S of GP Cytomegalovirus

A 
Commonly subclinical
Conjunctivitis
Lymphadenopathy
Latent, persistent infection in salivary gland
Abortions, stillbirths
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7
Q

Histo lesions of GP Cytomegalovirus

A

Eosinophilic intranuclear inclusions in epithelium of salivary glands

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8
Q

Prevention of GP Cytomegalovirus

A

Select stock known to be free of the virus

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9
Q

Family of GP AdV, Genus

A

Family: Adenovirus
Genus: Mastadenovirus

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10
Q

Caviid herpesvirus 1 c/s (Hsiung or Kapow virus, GP herpes-like virus)

A

Subclinical, occasional fetal wasting

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11
Q

Caviid herpesvirus 3 c/s (Guinea Pig X virus)

A

Unknown. Exp infection can result in hepatic necrosis

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12
Q

Equid herpes virus 1 subfamily

A

Alphaherpesvirinae

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13
Q

Equid herpes virus 1 genus

A

Varicellovirus

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14
Q

Equid herpes virus 1 subfamily C/S in GP

A

Neurologic (ataxia and paralysis), abortion/stillbirths

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15
Q

LCMV family, genus

A

Family: Arenaviridae, Genus:Arenavirus

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16
Q

Transmission of LCMV

A

Aerosol - insects, fomites, contaminated food/bedding

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17
Q

C/S of LCMV in GPs

A

Usually none

Meningitis and hind limb paralysis have been observed

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18
Q

Prevention and control of LCMV

A

Eliminate wild mice, parasites

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19
Q

Corona-like infection C/S in GP

A

Anorexia, diarrhea, low morbidity/mortality

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20
Q

Pathology of Corona-like infection in GP

A

Mucus throughout SI, blunting of villi

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21
Q

Paramyxoviridae in GPs (5)

A
  1. Human parainfluenza virus type 3
  2. Caviid parainfluenza virus 3
  3. Sendai virus
  4. Simian virus 5
  5. Murine pneumonia virus

All have no C/S

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22
Q

Human parainfluenza virus type 3 can sometimes cause what pahtology?

A

Interstitial pneumonia

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23
Q

Cavian Leukemia family

A

Retroviridae, Leukovirus

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24
Q

C/S of Cavian Leukemia

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A

Ruffled hair, pale MM, lethargy, lymphadenopathy, 2* infections

25
Theiler's murine encephalomyelitis virus family
Picornavirus
26
Theiler's murine encephalomyelitis virus transmission in GP
Fecal oral
27
Theiler's murine encephalomyelitis virus C/S in GP
Weight loss, paralysis
28
Etiology of GP chlamydial disease
Chlamydia caviae
29
Chlamydia caviae transmission
Ocular and nasal secretions
30
Chlamydia caviae C/S
``` Commonly subclinical Conjunctivitis with serous/purulent d/c, chemosis, keratitis, photophobia Rhinitis Genital tract infections Bronchopneumonia ```
31
Dx of Chlamydia caviae
Conjunctival scrapings
32
Chlamydia caviae prevention
Self-limiting. Has zoonotic potential
33
Etiology of GP dermatophytosis
Trichophyton mentagrophytes. Rarely Microsporum canis
34
C/S of GP dermatophytosis
Asymptomatic | Patchy alopecia, crusting, scaling
35
Dx of GP dermatophytosis
PAS, silver stain (GMS) | Culture on Sabouraud's agar
36
Tx of GP dermatophytosis
Miconazole (topical), fluconazole (systemic)
37
4 other misc GP fungal diseases
1. Histoplasma capsulatum (emaciation, hindlimb lameness, conjunctivitis) 2. Aspergillosis 3. Cryptococcus neoformans 4. Candida albicans
38
Hamster Polyomavirus causes which disease?
Transmissible Lymphoma
39
Transmission of Hamster Polyomavirus
Urine
40
C/S of hamster poloymavirus
Subclinical Multicentric lymphoma Trichoepitheliomas on face, feet, neck, back, flanks
41
Pathology of hamster poloymavirus
Lymphomas most commonly in intestines, mesentery, liver
42
Dx of hamster polyomavirus
Observation of trichoepitheliomas
43
Tx of hamster polyomavirus
Cull colony, decontaminate environment
44
Hamster parvovirus c/s
Subclinical Neonates and weanlings: runted with incisor abnormalities, domed cranium, potbellies Diarrhea, ataxia, mortality
45
Hamster parvovirus transmission
ingestion or inhalation
46
What kind of adenovirus naturally infects hamsters?
MAdv-1 and MAdv-2
47
Cricetid Herpesvirus (CrHV-1) C/S
Clinically silent, can cause SDAV in pet Cricetulus griseus
48
Transmission of Sendai virus in hamsters
Direct contact with infected rodents or fomites
49
Sendai virus C/S in hamsters
Subclinical Death in suckling hamsters Death with pulmonary lesions in Chinese hamsters
50
Pathology of Sendai virus
Consolidation of lung lobes
51
Prevention of Sendai virus
House hamsters in rooms separate from other rodents
52
LCMV in hamsters
Natural reservoir is mice, but hamsters are a highly susceptible secondary reservoir
53
LCMV transmission in hamsters
Verticla and horizontal - shedding occurs in urine, saliva, feces, milk, semen
54
LCMV C/S in hamsters
Acute: No C/S Chronic: Progressive wasting - hunched, weight loss, blepharitis
55
Pathology of LCMV in hamsters
Lymphocytic infiltration of visceral organs, vasculitis, glomerulitis, influenza-like symptoms, subclinical
56
Prevention and control of LCMV in hamsters
Purchase LCMV-negative hamsters | Pest control
57
Hamster dermatophyte
Trichophyton mentagrophytes (Djungarian hamsters)
58
Tx of hamster dermatophyte
Not effective, can try griseofulvin or topicals

Yale Residency - Rabbits, Guinea Pigs, Misc. Rodents (18 decks)

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