Anaplerotic and PPP

Question 1

pyruvate carboxylase

Answer 1

pyruvate —> oxaloacetate
requires CO2
activated by AcCoA
reversible

Question 2

Phosphoenol pyruvate carboxy kinase

Answer 2

oxaloacetate —> phosphoenol pyruvate
GTP —> GDP
released CO2
reversible

Question 3

Phosphoenol pyruvate carboxylase

Answer 3

Phosphoenolpyruvate —> oxaloacetate
requires HCO3-
releases Pi
occurs in plants

Question 4

malic enzyme

Answer 4

pyruvate —> malate
NADPH + H+ —> NADP+
requires CO2
reversible

Question 5

ribose 5 phosphate epimerase

Answer 5

ribulose 5 P —> xylulose 5 P

reversible

Question 6

ribose 5 isomerase

Answer 6

ribulose 5 P —> ribose 5 P

reversible

Question 7

transketolase TPP

Answer 7

xylulose 5 P + ribose 5 P —> glyceraldehyde 3 P + sedeheptulose 7 P
reversible

Question 8

transaldolase

Answer 8

sedoheptulose 7 P + glyceraldehyde 3 P —> fructose 6 P + erythrose 4 P
reversible

Question 9

transketolase

Answer 9

erythrose 4 P + xylulose 5 P —> fructose 6 P + glyceraldehyde 3 P
reversible

Question 10

triose phosphate isomerase

Answer 10

glyceraldehyde 3 P —> dihydroxy acetone phosphate

reversible

Question 11

aldolase

Answer 11

glyceraldehyde 3 P + dihydroxyacetone P —> fructose 1,6 bisP
reversible

Question 12

fructose 1,6 bisphosphotase

Answer 12

fructose 1,6 bisP —> fructose 6 P
requires water
releases Pi

Question 13

phosphogluco isomerase

Answer 13

fructose 6 P —> glucose 6 P

Question 14

glucose 6 phosphate dehydrogenase

Answer 14

glucose 6 P —> gluconolactone 6 P
NADP+ —> NADPH + H+
reversible

Question 15

lactonase

Answer 15

gluconolactone 6 P —> gluconate 6 P

Question 16

gluconate 6 phosphate dehydrogenase

Answer 16

gluconate 6 P —> ribulose 5 P
NADP+ —> NADPH + H+
releases CO2