12. Total Protein Flashcards

1
Q

Albumin is what % of total protein? `

A

60%

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2
Q

globulin is what % of total protein? `

A

40%

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3
Q

formed in the liver and therefore measure liver function

A

albumin

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4
Q

main purpose of albumin is maintain

A

osmotic pressures and transport substances (drugs, hormones, and enzymes)

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5
Q

albumin also increases

A

solubility of materials in blood

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6
Q

some globulins are made in the liver, but mostly are made in the

A

reticuloendothelial system

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7
Q

acute phase protein elevated in inflammation, malignancy, or infection

A

alpha1-antitrypsin

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8
Q

90% of alpha1-globulins are

A

alpha1-antitrypsin

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9
Q

lack of alpha1-antitrypsin indicates early onset

A

emphysema

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10
Q

haptoglobins, prothrombin, ceruloplasmin, and cholinesterase

A

alpha2-globulins

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11
Q

ceruloplasmin is used for

A

copper transport

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12
Q

lipoproteins, transferrin, plasminogen, and compliment are

A

beta1-globulins

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13
Q

beta2-globulin is primarily

A

fibrinogen

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14
Q

immune globulins, aka antibodies

A

gammaglobulins

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15
Q

seperates the various components out of serum

A

serum protein electrophoresis (SPEP)

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16
Q

an electric current is passed through the sample causing the charged proteins to migrate into a pattern descriptive of certain diseases

A

serum protein electrophoresis (SPEP)

17
Q

usually ordered if there is a spike at the

A

immunoglobin level

18
Q

may represent multiple myeloma or Waldenstrom’s macroglobulinemia

A

monoclonal spikes

19
Q

seen in cirrhosis, nephrotic syndrome, chronic or acute inflammation

A

polyclonal spike