7: Malabsorption Flashcards

1
Q

What is malabsorption?

A

Defective mucosal absorption of nutrients and fluids

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2
Q

What disease, associated with gluten intolerance, can cause malabsorption?

A

Coeliac disease

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3
Q

Which inflammatory bowel diseases causes malabsorption?

A

Crohn’s disease

Ulcerative colitis to a lesser extent

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4
Q

Patients may present with malabsorption post-___.

A

infection

surgery

chemo/radiotherapy…

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5
Q

Which drugs are designed to cause malabsorption?

A

Fat blockers

e.g Orlistat / Alli

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6
Q

Obstruction of the ___ can cause malnutrition.

A

gallbladder

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7
Q

Malabsorption of which food groups causes weight loss?

A

Protein

Fat

Carbohydrate

Vitamins & Minerals

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8
Q

Removal of which organ can cause protein malabsorption?

A

Stomach

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9
Q

Which enzymes digest protein in the stomach?

A

Pepsin

Trypsin

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10
Q

Deficiency of which enzyme, secreted by the pancreas, can cause carbohydrate malabsorption?

A

Alpha amylase

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11
Q

Which surgical procedures intentionally cause malabsorption?

A

Bariatric surgery

e.g gastric bypass, band

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12
Q

After which cancer treatment may patients develop malabsorption?

Why?

A

Chemotherapy

Kills mucosal cells temporarily

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13
Q

What should be asked about in the history phase of a consultation with someone who has suspected malabsorption?

A

Past medical history

Travel

Alcohol

Drugs

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14
Q

Easy bruising and gingival hyperplasia suggest a ___ deficiency.

A

Vitamin C / K

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15
Q

People with inflammatory bowel disease are likely to present with systemic manifestations as well.

Which signs of IBD can be seen on the tongue and lips?

A

Glossitis (tongue)

Angular stomatitis (lips)

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16
Q

What does iron deficiency cause in nails?

A

Spooning

(Koilonychia)

17
Q

What are some investigations you would do for suspected malabsorption?

A

Full blood count

Coagulation test

LFTs

Albumin

U&Es

Stool culture

18
Q

What investigation involves shoving a camera into someone and possibly taking a biopsy as well?

A

Endoscopy