History Flashcards

1
Q

Ethnicity?

A

sickle cell affects mainly west African and Afro-Caribbean patients.

Thalassaemias and G6PDH deficiency affect Mediterranean, east Asian and African.

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2
Q

are they pregnant?

A

Intrahepatic cholestasis of pregnancy, pre-eclampsia with HELLP syndrome or acute fatty liver of pregnancy.

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3
Q

RUQ discomfort, nausea, vomiting, pruritus?

A

hepatitis

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4
Q

Fever or diarrhoea?

A

May be present if liver is infected.

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5
Q

Steatorrhoea, dark urine and pruritus?

A

obstruction to biliary flow.

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6
Q

weight loss, fever, night sweats?

A

could indicate a malignancy of the liver, bile duct or pancreas.

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7
Q

bronzed skin, signs of DM?

A

haemochromatosis.

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8
Q

exposure to outdoor water / sewage?

A

Risk factor for leptospirosis.

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9
Q

PMH drugs that cause intravascular haemolysis?

A

sulphonamides, aspirin in G6PDH patients

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10
Q

PMH drug that causes autoimmune extravascular haemolysis?

A

methyldopa

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11
Q

PMH drugs that cause hepatitis?

A

paracetamol OD

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12
Q

PMH drugs that cause cholestasis?

A

co-amoxiclav

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13
Q

family history?

A

Gilberts syndrome, haemochromatosis, Wilsons disease, sickle cell disease, thalassaemia, hereditary spherocytosis, G6PDH deficiency

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14
Q

social history?

A

Alcohol consumption? IV drug use? Unprotected sex? Foreign travel? Tattoos?

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