9.4 GFR And Rnal Clearance Flashcards
1
Q
Define GFR
A
Amount of fluid filtered from the glomeruli into bowman’s capsule per unit time (mL/min)
Sum of filtration rate of all functioning nephrons
2
Q
Define freely filtered substance
A
For substance x the concentration of x in the glomeruli plasma = concentration of x in bowman’s capsule filtate
3
Q
Calculation of GFR for Inulin
A
GFR = renal clearance of Inulin
C = u x v / p
4
Q
List 5 properties of Inulin which makes it an ideal marker for GFR calculation
A
Freely filtered
Not reabsorbed
Not secreted
Non toxic
Can be measured in plasma and urine
5
Q
Clearance =
A
V x U / p
6
Q
If sodium is freely filtered at glomrulus and has a decreased renal clearance what can be deducted
A
High reabsorption in the nephron
7
Q
If a substance has a higher renal clearance thwt Inulin
A
High secretion
