9.7 Structure of Genes and the Human Genome Flashcards Preview

Foundations Exam 3 > 9.7 Structure of Genes and the Human Genome > Flashcards

Flashcards in 9.7 Structure of Genes and the Human Genome Deck (14):
1

What are the three main categories in the composition of the human genome?

1. genes encoding proteins/structural RNA
2. Repetitive DNA
3. Other non-repetitive DNA

2

beta-globin genes are an example of _________________________ (what category in the composition of the human genome)

duplicated protein coding genes

3

_________ are tandemly repeated structural RNA genes ribosomal RNA genes
another word for simple tandem repeats

satellite DNA

4

blocks of short repeated sequences back to back to back (many repeats) are called:

simple tandem repeats

5

a type of simple tandem repeat is:

short variable repeats

6

______________ contribute to DNA sequencing

short variable repeats

7

larger repeated repeat sequences scattered through genomic DNA are called:

interspersed

8

LINES stand for:

long interspersed repeats

9

SINEs stand for:

short interspersed repeats

10

an example of a SINE (and most abundant) is the ____ __________

Alu element

11

LINEs and SINEs are related to ______ _______, thus they can move in and out of DNA. Most are inactive, but some can move and insert into a gene.

transposable elements

12

in __________, a LINE inserts into the gene coding for Factor 8 (coagulation factor

hemophilia

13

In ________ ______, a triplet region causes a poly-glutamate stretch, causing aggregates of a protein that interferes with brain function. What type of sequence category is this?

Huntingtons disease, short variable repeat (short random repeats)

14

In ________, the nucleotides CGG are repeated around 200 times in a gene. CGG can be methylated and thus, there is decrease in transcription of the gene and no ______ __ is synthesized

Fragile-X syndrome, fragile-X