Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Revision > Haematology > Flashcards

Haematology Flashcards

1
Q

Haemophilia A

A

Causes hemarthrosis without trauma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

VTE

A

Anticoagulate with warfarin for 3 months is provoked and 6 months if unprovoked

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Burkitt lymphoma

A

Starry sky appearance on lymph node biopsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Sequestration crisis

A

Occurs in sickle cell anaemia and causes splenomegaly with abdominal pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Beta-thalassaemia trait

A
  • microcytic anaemia
  • raised HbA2
  • lethargy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

C-myc translocation

A

Genetic change in Burkitt’s lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Antiphospholipid syndrome

A
  • prolonged APTT
  • history of VTE, PE and miscarriage
  • elevated anticardiolipin antibody
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Antiphospholipid syndrome (pregnancy)

A

Anticoagulate with aspirin and enoxaparin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Irradiated blood products

A

Used to avoid transfusion-associated graft vs host disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Tranaxamic acid

A

When given in major haemorrhage give IV bolus and then slow infusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Blood transfusion

A

Give if haemodynamically unstable or Hb is less than 70g/L

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Neutropenic sepsis

A

Empirical treatment with piperacillin and tazobactam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Blood transfusion complications

A
  • iron overload
  • ARDS
  • hyperkalaemia
  • clotting abnormalities
  • febrile reaction
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Multiple myeloma

A

Rain drop skill or pepperpot skull seen on imaging

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Disseminated intravascular dissemination

A

Give fresh frozen plasma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Vitamin B12 deficiency

A

Causes macrocytic anaemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

G6PD

A
  • pallor
  • jaundice
  • haemolytic anaemia
  • previous URTI
  • Heinz bodies
18
Q

Multiple myeloma

A

Typically causes hypercalcaemia, pancytopenia and AKI

19
Q

Reed-Sternberg cells

A

Have mirror image nuclei and are seen in Hodgkin’s lymphoma

20
Q

Stage two Hodgkin’s lymphoma

A

Tow or more lymph nodes on the same side of the diaphragm

21
Q

Philadelphia chromosome

A

t(9;22) associated with CML

22
Q

Idarucizumab

A

Reversible agent for dabigatran

23
Q

Hereditary spherocytosis

A

-jaundice, fatigue and splenomegaly in haemolytic crisis

24
Q

Cryoprecipitate

A

Given in major haemorrhage when the fibrinogen level is low

25
Q

Sickle cell anaemia

A

Normocytic anaemia with Howell-Jolly bodies

26
Q

Autoimmune haemolytic anaemia

A

Can be caused by SLE

27
Q

DVT in pregnancy

A

Tend to give subcutaneous low molecular weight heparin

28
Q

Tumour lysis syndrome

A

Can give allopurinol or rasburicase prior to chemo to reduce the risk

29
Q

Platelet transfusion

A

High risk of bacterial contamination compared to other blood products

30
Q

Non-haemolytic febrile transfusion syndrome

A

Pause transfusion and assess for risk and if safe give IV paracetamol and continue

31
Q

Coeliac disease

A

Can cause target cells and Howell-Jolly bodies due to hyposplenism

32
Q

Polycythaemia rubra vera

A

Around 5-15% progress to myelofibrosis or AML

33
Q

Beta thalassaemia

A

Microcytic, hypochromic anaemia

  • basophilic stippling
  • occasional target cells
34
Q

Lead poisoning

A
  • gastrointestinal and neuropsychiatric symptoms
  • anaemia
  • blue line on gum margin
35
Q

Aplastic crisis

A

Seen in sickle cell disease often related to parvovirus infection

36
Q

Haemophilia A

A

Factor VIII associated with 90% of all haemophilia

37
Q

Acute haemolytic transfusion reaction

A

Combs test

-RBC destruction by IgM

38
Q

Dabigatran

A

Direct thrombin inhibitor

39
Q

Won willebrands disease

A
  • prolonged bleeding time
  • normal platelet count
  • prolonged APTT
40
Q

Factor V Leiden

A

Also known as activated protein C resistance and the most common inherited thrombophilia

41
Q

Antiphospholipid syndrome

A

History of clotting and bleeding

-need aspirin and LMWH in pregnancy

Revision (18 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions