A1.2 - nucleic acids Flashcards

1
Q

antiparallel

A

when 2 strands are parallel but run in opposite direction to each other

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2
Q

centrifugation

A

spinning a sample very quickly to separate the components based on density

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3
Q

codon

A

a group of 3 RNA nucleotide that contain info for the ribosome to insert an amino acid to the polypeptide chain during protein synthesis

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4
Q

genetic code

A

each triplet codon has info used to add an amino acid to the growing polypeptide chain

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5
Q

linker DNA

A

DNA located between nucleosomes

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6
Q

octamer

A

group of 8 histone proteins in the core of each nucleosome

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7
Q

pentose

A

sugar molecules containing 5 carbon atoms

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8
Q

nucleotide

A

a structure composed of a phosphate group, pentose sugar and base joined by covalent bonds

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9
Q

what are the characteristics of DNA?

A
  • located in living organisms
  • double stranded
  • deoxyribose sugar
  • adenine, guanine, thymine, cytosine
  • helical double helix shape with 2 antiparallel strands
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10
Q

what are the characteristics of RNA?

A
  • found in viruses
  • single stranded
  • ribose sugar
  • adenine, guanine, cytosine, uracil
  • variety of forms (mRNA, tRNA, rRNA)
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11
Q

how are nucleotides joined in DNA and RNA?

A

covalent sugar-phosphate bond formed by condensation reactions where water is released
- between pentose on one nucleotide and phosphate group of another

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12
Q

what are the bases?

A
  • adenine
  • cytosine
  • guanine
  • thymine or uracil
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13
Q

DNA

A

long-term hereditary storage molecules

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14
Q

mRNA

A

messenger RNA leaves the nucleus and brings genetic info to the ribosome during transcription

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15
Q

tRNA

A

transfer RNA brings the correct amino acid to the growing polypeptide chain during translation

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16
Q

rRNA

A

ribosomal RNA carries out translation in the ribosomes

17
Q

ATP

A

single nucleotide nucleic acid with adenine, ribose and 3 phosphate groups used as a short-term chemical energy store

18
Q

what is complementary base pairing?

A
  • specific bases only pair with each other due to hydrogen bonding
  • A and T/U
  • G and C
19
Q

how does complementary base pairing allow genetic information to be 1) replicated 2) expressed?

A

replicated - separating strands of DNA and allowing free DNA nucleotides to base pair with unmatched nucleotides forms an exact cope of the molecule
expressed - separating strands of DNA and allowing free RNA nucleotides to base pair with unmatched nucleotides forms an RNA copy of one strand of DNA which can be used by ribosomes for protein synthesis

20
Q

how is DNA diverse and how does it contribute to its role?

A
  • molecules can have any length and any base sequence
  • allows DNA to store huge amounts of data in the genetic code with great economy, contributing to diversity of organisms
21
Q

what evidence is there for a universal common ancestor?

A

universal genetic code - same codons code for the same amino acids in all organisms
conservation of genetic code - life on earth has evolved from a common ancestor