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Bacteriology > Abx and resistances > Flashcards

Abx and resistances Flashcards

1
Q

Enterbacterales Tier 1 (not including MYSPHECK, shigella, or salmonella)

A

Ampicillin, Cefazolin, Cefotaxime, ceftriaxone, amoxicillin-clavulanate, ampicillin-sulbactam, Piperacillin-tazobactam, Gentamicin, Ciprofloxacin, Levofloxacin, Trimethoprim-sulfamethoxazole

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2
Q

Enterbacterales Tier 2 (not including shigella, or salmonella)

A

Cefuroxime, Cefepime, Ertapenem, Imipenem, Meropenem, Tobramycin, Amikacin, Cefotetan, Cefoxitin, Tetracycline (indicator for doxy and mino)

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3
Q

MYSPHECK tier 1

A

Cefepime

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4
Q

What is cefazolin a surrogate test for?

A

oral cephalosporins (ex: cephalexin, cefuroxime, cefdinir, cefixime)

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5
Q

EColi urinary tract tier 3

A

fosfomycin

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6
Q

Tier 3 non-

A
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7
Q

Tier 3 Enterbacterales (not shigella/salmonella)

A

Cefiderocol, Ceftaz-avibactam, imipenem-relebactam, meropenem-vaborbactam

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8
Q

What drugs active against Enterbacterales cannot penetrate the blood brain barrier?

A

first and second gen cephalosporins and cephalomycins, doripenem, ertapenem, imipenem, clindamycin, lefamulin, macrolides, tetracyclines, fluoroquinolones

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9
Q

What is a cephalosporin that can cross the blood brain barrier??

A

ceftriaxone (3rd generation cephalosporin)

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10
Q

group 2d carbapenemases

A

OXA Beta-lactamases

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11
Q

group 2f serine carbapenemases

A

KPC, SME, NMC-A, IMI, GES

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12
Q

plasmid-encoded metallo-beta-lactamases

A

IMP, VIM, NDM

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13
Q

Organisms with chromosomally encoded metallo-beta-lactamases

A

Stenotrophomonas maltophilia, bacillus anthracis, bacillus fragilis

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14
Q

Inactivation of what porin is associated with carbapenem resistance in PSAU?

A

OprD

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15
Q

Which organisms chromosomally encode ampC

A

HECK-Yes
Hafnia alvei, Enterobacter cloacae, Citrobacter freundii , Klebsiella aerogenes, Yersinia enterocolitica

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16
Q

Which carbapenem can not penetrate CSF?

A

ertapenem

17
Q

Which enterococcus is resistant to all carbapenems?

A

Enterococcus faecium

18
Q

What carbapenem relibably inhibits Enterococcus faecalis?

A

imipenem

19
Q

Tier 1 PSAU antibiotic s

A

Ceftazidime, cefepime, piperacillin-tazobactam, tobramycin, ciprofloxacin, levofloxacin

20
Q

Tier 2 PSAU antibiotics

A

imipenem, meropenem

Bacteriology (4 decks)

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