Acute Inflammatory Polyneuropathy (Guillain-Barré Syndrome)

Question 1

It is is an ____ damage of ________.

Answer 1

autoimmune

multiple peripheral nerves.

Question 2

T/F there is CNS involvement.

Answer 2

F

Question 3

A circulating ____ attacks the______ of the peripheral nerves, removing their _____-

Answer 3

antibody
myelin sheaths
insulation.

Question 4

GBS is associated with _______ infection.

Answer 4

Campylobacter jejuni

Question 5

“What Is the Most Likely Diagnosis?” 2 CxFx

Answer 5

weakness in the legs that ascends from the feet and moves toward the chest,
+
loss of DTRs.

Question 6

a few Pt have this sign

Answer 6

mild sensory disturbance.

Question 7

when GBS hits the diaphragm, it is associated with

Answer 7

respiratory muscle weakness

Question 8

This other manifestations car occur

Answer 8

Autonomic dysfunction
+
hypotension, hypertension, or tachycardia

Question 9

The most specific diagnostic test is

Answer 9

nerve conduction studies/electromyography.

These will show a decrease in the propagation of electrical impulses along the nerves, but it takes 1–2 weeks to become abnormal

Question 10

CSF shows

Answer 10

increased protein with a normal cell count

Question 11

Tests of Respiratory Muscle Involvement?

show?

Answer 11

PFTs. tell who might die from GBS

When the diaphragm is involved, there is a decrease in forced vital capacity and peak inspiratory pressure. Inspiration is the “active” part of breathing and the patient loses the strength to inhale.

Question 12

Death from GBS, how, why?

Answer 12

from dysautonomia and respiratory failure

Question 13

Treatment

Answer 13

Intravenous immunoglobulin (IVIG) or plasmapheresis are equal in efficacy

Question 14

when to use Prednisone

Answer 14

Never in GBS, is a wrong answer.

Question 15

what about Combining IVIG and plasmapheresis

Answer 15

wrong answer.