Acute Liver Failure Flashcards

1
Q

What is Acute Liver Failure?

A

Life-threatening severe liver injury occurring within days to 6 months after insult

Rapid increase in AST/ALT, AMS, coagulopathy

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2
Q

What causes ALF?

A

Almost 50% cases are drug-induced (majority acetaminophen)

Other causes:
* Viral hepatitis
* autoimmune
* hypoxia
* ALF of pregnancy
* HELLP

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3
Q

What are the s/s of ALF?

A
  • Jaundice
  • nausea
  • RUQ pain
  • cerebral edema
  • encephalopathy
  • multi-organ failure
  • death

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4
Q

What is the treatment for ALF?

A
  • Treat the cause
  • supportive care
  • liver transplant
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