All references

Question 1

Dewannieux et al. 2003

Answer 1

Showed that Alus can retrotranspose by diverting the enzymatic machinery of LINEs by studying mobility of marked Alu sequences in HeLa cells

Question 2

Dewannieux et al. 2005

Answer 2

Showed that B1 and B2 SINEs can use the enzymatic machinery of LINEs (shown to be mobilised by murine LINEs)

Question 3

McClintock 1940s and 1965

Answer 3

Barbara McClintock discovered TEs (1940s) and was the first scientist to suggest that they might play regulatory roles (1965), determining which genes are turned on and when this activation takes placeUl

Question 4

Ullu and Tschudi, 1984

Answer 4

Showed that Alu repeat family of SINEs is a retrotransposon of 7SL RNA

( We suggest that mammalian Alu sequences were derived from 7SL RNA (or DNA) by a deletion of the central 7SL-specific sequence, and are therefore processed 7SL RNA genes.)