Amide Hydrolysis Flashcards
1
Q
What happens in this reaction?
A
An Amide is hydrolysed by water to form a carboxylic acid and Amine
2
Q
What are the enzymes involved?
A
Amidases
3
Q
Where does the metabolism occur?
A
Liver and Kidney
4
Q
What is the fact about this reaction? Hint: Amides are stable
A
Amides are the most stable derivatives of caboxylic acids, therefore hydrolysis is very hard to initiate. When the reaction does start, it is a very slow process.
