amoldipine Flashcards
1
Q
clinical use
A
SELECTIVE v-gated Ca2+ channel antagonist (CCB) which block Ca 2+ entry in response to depolarisation to inhibit constriction of arterioles; peripheral arterial vasodilator
2
Q
site of action
A
vascular smooth muscle (surrounds blood vessels)
3
Q
mech of beneficial action
A
decreases TPR via vasodilation, thus decreasing BP as well as increasing supply of blood & O to the heart while reducing its workload
4
Q
common/serious side effects
A
common: ankle swelling (oedema, constipation, tachycardia, and headache
serious:
