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Pharmacology > Analgesics and Antiemetics > Flashcards

Analgesics and Antiemetics Flashcards

1
Q

What nociceptive pain?

A

Acute

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2
Q

What is neuropathic pain?

A

Chronic

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3
Q

What is allodynia?

A

Pain from a stimulus that does not normally cause pain

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4
Q

What is parasthesis?

A

Painful feelings with no apparent stimulus eg. pins and needles

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5
Q

What are the 4 types of analgesics?

A

Opioids
Antidepressants
Antiepileptics
Local anaesthetics

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6
Q

Where do opioids act?

A

Spinal cord and CNS

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7
Q

What is the 3 step mechanism of opioids?

A

Decrease neurotransmitter release
Block postsynaptic receptors
Activate inhibitory pathways

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8
Q

What are the advantages of opioids?

A

Variety of routes
Range of effect durations
Highly effective

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9
Q

What are the disadvantages of opioids?

A

Interactions
Contradictions
Side effects

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10
Q

What are the side effects of opioids?

A 
Nausea
Constipation
Drowsiness
Respiratory depression
Hypotension
Sedation
Dependancy
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11
Q

What are the two types of anti depressants and analgesics?

A

Serotonin and noradrenaline reuptake inhibitors (SNRI)

Selective serotonin reuptake inhibitors (SSRI)

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12
Q

What are examples of serotonin and noradrenaline reuptake inhibitors?

A

Ventafaxine

Duloxetine

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13
Q

What are examples of selective serotonin reuptake inhibitors?

A

Paroxetine

Citalopram

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14
Q

What is duloxetine prescribed for?

A

Peripheral neuropathy particularly diabetic

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15
Q

What are the side effects of duloxetine?

A

Nausea
Somnolence
Insomnia
Dizziness

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16
Q

What is venlafaxine prescribed for?

A

Diabetic neuropathy

17
Q

What are the side effects of venlafaxine?

A

Nausea
Sedation
Headache
Dizziness

18
Q

What are cautions/ contraindications of serotonin and noradrenaline reuptake inhibitors?

A 
Epilepsy
Cardiac disease
Daibetes
Glaucoma
Pregnancy
19
Q

What is the mechanism of anti epileptic agents?

A

Inhibit voltage gated Na+ channels
Inhibit voltage gated Ca2+ channels
Inhibit GABA & Glycerine receptor

Pharmacology (7 decks)

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