Anatomy Nervous and Muscle Flashcards
Agonist(prime mover)
Muscle that contracts to produce a particular movement
Antagonist
Muscle who’s actions oppose those of the agonist, if the Agonist produces extension, the antagonist produces flexion
Synergist
a muscle that assists the agonist in performing its action
Levers (p. 309)
First class lever-has a fulcrum in the middle, Between effort and the resistance, example scissors Second class lever-between the fulcrum and the applied effort, example lifting the handles of a wheelbarrow Third class lever-an effort is applied between the resistance and the fulcrum, as when picking up a small object with a pair of forceps
tendon
Attaches the muscle to bone, Skin, or another muscle, tendons usually have thick, cord like structure
aponeurosis
A tendon that forms a thin, flat and sheet
origin(muscle)
The less mobile attachment of a muscle, for example the superior biceps
insertion(muscle)
The more mobile attachment of the muscle, for example the inferior biceps
What are the various functions of the muscular system?
- Body movement
- Maintenance of posture
- Temperature regulation
- Storage and movement of materials
- Support
Diagram and describe the arrangement of muscle with its connective tissue coverings.
The three connective tissue layers are the epimysium, perimysium, endomysium, p. 290
Epimysium
Is a layer of dense irregular connective tissue that surrounds the whole skeletal muscle.
Perimysium
Surrounds the fascicles
endomysium
Is the innermost connective tissue layer, surrounds each muscle fiber
Muscle fiber
Single muscle cell, metabolic activities, contraction
Diagram and describe how the nerve impulses to the point of the beginning of contraction in skeletal muscle tissue
Each motor neuron has a long extension called an axon or nerve fiber. an axon of a motor neuron transmits a nerve impulse to a muscle fiber. The Axon travels through the epimysium and perimysium and enters the endomysium where it delivers a nerve impulse to an individual muscle fiber. (p.292)
ATP
Adenosine triphosphate, Energy
sarcolemma
The plasma membrane of a skeletal muscle fiber
Satellite cells
Embryonic like cells in adult skeletal muscle tissue, if skeletal muscle is injured some satellite cells maybe stimulated to assist and repair, left over myoblasts which did not fuse with muscle fibers.
sarcoplasmic reticulum
Internal membrane complex, is similar to the smooth endoplasmic reticulum of other cells, stores calcium ions needed to initiate muscle contraction.
Neuromuscular junction
The junction between the axon in the muscle fiber, the point where a motor neuron meet a skeletal muscle fiber
Thick filaments
Fine protein myofilaments composed of bundles of myosin, bind to thin filament and cause contraction
Thin filaments
Fine protein myofilaments composed of actin, troponin, and tropomyosin, thick filaments bind to it and cause contraction
Actin
Double-stranded contractile protein, binding site for myosin to shorten a sarcomere
Myosin
Protein, consists of two intertwined strands
sarcomere
The functional contractile unit of a skeletal muscle fiber, defined as the distance from one Z disk to the next to adjacent Z disc
Terminal cisternae
Site of calcium ion release to promote muscle contraction, expanded ends of the sarcoplasmic reticulum that are in contact with the transverse tubules
Transverse tubule
Quickly transports a muscle impulse from the sarcolemma through the entire muscle fiber, tubular extensions of the sarcolemma into the sarcoplasm contact the terminal cistern wrapped around myofibrils
Myofibrils
Contain myofilaments that are responsible for muscle contraction, organized bundles of myofilaments
Triad
Structure formed by the two terminal cisternae and the centrally placed T tubule
tropomyosin
Covers the active sites on Actin, preventing myosin from binding to actin when muscle fibers is at rest, double-stranded regulatory protein
Troponin
Three functions
- attaches to actin to anchor itself in place
- attaches to tropomyosin to hold it in place over the surface of the actin
- provides a binding site for calcium ions
Myofilaments
Bundles of short filaments which create myofibrils
Cross bridge
Formed by myosin heads during a contraction by binding thick filaments to actin in the thin filaments
A band(dark band)
Dark band, Contains the entire thick filament
I band (light band)
Light band, contains thin filaments but no thick filaments
H zone
Light, central region in the A band, is lighter shaded because only thick filaments are present
Z line
Then transverse protein structure in the center of the I band that serves as an attachment site for thin filament ends.
The sliding filament theory
When a muscle contracts, thick and thin filaments slide passed each other, and the sarcomere shortens.
Show how the banding pattern changes at full contraction(p.297)
- the width of the A band remains constant but the H zone disappears
- the Z discs in one sarcomere move closer together
- The sarcomere narrows or shortens in length
- that I bands narrow or shortening in length
Synaptic knob
Expanded tip of an axon of a neuron, when it nears the sarcolemma of a muscle fiber, it expands further to cover a relatively large surface area of the sarcolemma, the nerve impulse travels through the axon to the synaptic knob.
Synaptic cleft
Narrow space separating the synaptic knob and the motor end plate
Motor end plate
is a specialized region of the sarcolemma, it has folds and indentations to increase the membrane surface area covered by the synaptic knob
acetylcholine
Neurotransmitter which helps stimulate the muscle
acetylcholinesterase
An enzyme that resides in the synaptic cleft, Break sound molecules of ACH, needed so ACH will not continuously stimulate muscle
Diagram and describe the anatomy and contraction of skeletal muscle tissue(p.302)
- A nerve impulse causes ACH release at a neuromuscular junction. ACH binds receptors on the motor end plate, initiating a muscle impulse.
- the muscle impulse spreads quickly along the sarcolemma and into the muscle fiber along T tubule membranes, causing calcium ions to be released into the sarcoplasm
- calcium ions bind to troponin, causing tropomyosin to move and expose active sites on Actin, myosin heads attached to the actin and form cross bridges.
- myosin heads go through cyclic “attach-pivot-detach-return” events as the thin filaments are pulled passed the thick filaments, ATP is required to detach the myosin heads complete the sequence of cyclic events. The sarcomere shortens, and the muscle contracts. The cyclic events continue as long as calcium ions remain bound to the troponin.
- calcium ions are moved back into the sarcoplasmic reticulum by ATP driven ion pumps to reduce calcium concentration and the sarcoplasm, leading to relaxation. Termination of the muscle impulse results in the passive sliding of myofilaments back to their original state.
Motor unit
Composed of a single motor neuron and all of the muscle fibers it controls, Motor neurons initiate the process of muscle contraction in a single muscle fiber
All or none
Principle which states that a muscle fiber either contracts completely or does not contract at all
Considering “the all or none” rule of muscle contraction, How is it that we are able to have smooth and refined body movements
When a motor unit is stimulated all its fibers contractors same time the total force exerted by the muscle depends on the number of activated units if more motor units are activator create more muscle fibers contract in greater force exerted payments and require less force need fewer activated motor units. That’s although the muscle fibers ove the all or none principle, the force and precision muscle movement can be very, depending on how many muscle fibers and motor units activated
Contrast fast fibers, slow fibers and intermediate fibers in muscle(chart p. 304)
Fast fibers-most prevalent scout of muscle fiber type, Largest in diameter, Contain fast ATPase, provide power and speed, can only contract for short burst because ATP is provided through anaerobic cellular respiration, these fibers appear white because of the relative lack of myoglobin
- slow fibers- Half the diameter of other skeletal muscle fibers and contains slow ATPase, produce contractions that are slower and less powerful, but can contract over long periods of time without fatigue because ATP is supplied primarily through aerobic cellular respiration, these fibers are dark red because of the presence of large amounts of myoglobin
- intermediate fibers-least numerous of the skeletal muscle fiber types, intermediate size and contain fast ATPase, fast powerful contraction with a ATP are lighter red because they do contain some myoglobin
Unipennate muscle
All the muscle fibers are on the same side of the tendon
Bipennate muscle
The most common type, Has muscle fibers on both sides of the tendon
Multipennate muscle
Has branches of the tendon within the muscle, example the triangular deltoid
Parallel muscle(biceps, Abdomen, mandible)
Has fascicles that run parallel to its long axis, each muscle fiber in this type of skeletal muscle exhibits the functional characteristics of the entire parallel muscle, muscle shortens when it contracts and the body increases in diameter, high endurance but are not as strong as other muscle types
What happens during muscle atrophy and muscle hypertrophy
Atrophy is it wasting away of tissue that results in a reduction in muscle size, tone, and power
Hypertrophy is an increasing muscle size, It does not result in an increase in muscle fiber number, however does result in an increasing number of myofibrils per fiber in fast fibers
Why might atrophy be permanent
Individuals who suffer damage to the nervous system or paralyzed by spinal injuries, although the muscle atrophy is initially reversible, dead or dying muscle fibers are not replaced. When extreme atrophy occurs, the loss of gross muscle function is permanent.
Convergent muscle
Triangular muscle with common attachment site, directional pull of muscle can be changed, does not pull as hard as equal size parallel muscle
Sphincter(Circular)
Concentricly arranged around an opening or recess, contraction of the muscle closes off the opening
Homeostasis
consistent internal environment
It’s a muscle can only contract(shorten in length) explain how it is that we can push an object. Give an example.
p.308