Anatomy Of Immune System

Question 1

IL-7 produces what kind of cell

Answer 1

T cell

Question 2

IL-15 produces what type of cell

Answer 2

Natural killer cell

Question 3

What do common gamma chains do

Answer 3

They are receptors for the interleukins

Question 4

Where it’s the gene for the gamma chain located

Answer 4

X chromosome

Question 5

What it’s the indication for SCID

Answer 5

Absence of T cells

Question 6

Measure the total immunoglobulin tigers in serum

Answer 6

Nephelometry

Question 7

Measures specific immunoglobulins or antigens in serum

Answer 7

ELISA

Question 8

Assesses presence of tissue antigens or serum immunoglobins

Answer 8

Immunofluoresccence

Question 9

Assesses presence and phenotype of peripheral blood or tissues

Answer 9

Flow cytometry

Question 10

In flow cytometry of SSC vs FSC, what would be in the far left corner? What about far right

Answer 10

Granulocytes, monocytes

Question 11

What are the self antigens fo T helper cells

Answer 11

CD4, TCR, CD3, CD28, MHC1

Question 12

What are the self antigens of CTL

Answer 12

CD8, TCR, CD3, CD28, MHC

Question 13

What are the self antigens of B cell

Answer 13

BCR, MHC I, MHC II, CD20, CD19, CD40

Question 14

MACROPHAGES AND DENDRITIC CELLS EXPRESS

Answer 14

MHC I AND MHC II

Question 15

What are the costimulatory molecules on Macrophages and Denderitic cells

Answer 15

CD 80 and CD86

Question 16

What is used to identify NK on flow cytometry

Answer 16

CD56

Question 17

What is the effect of MHC I receptors on NK cells

Answer 17

Raises threshold for activation

Question 18

What do activated NK secrete

Answer 18

IFN-gamma (Th1)

Question 19

CD56 is associated with what cells

Answer 19

Natural Killer Cells

Question 20

IFN-gamma stimulates the cell with what surface markers

Answer 20

MHC-1

Question 21

What cells are going to still be present in a gamma chain deficiency

Answer 21

B cells (nonfunctional)

Question 22

What deficiency is associated with the absence of all lymphocytes

Answer 22

ADA

Question 23

What does the gamma chain receptor do?

Answer 23

Respond to Il-7 and IL-15

Question 24

What do CD80 and CD86 bing to

Answer 24

CD28

Question 25

IFN-gamma promotes

Answer 25

MHC-I

Question 26

Vaccines are ______ immunization

Answer 26

Active

Question 27

Rtuximab binds to what to treat autoimmune disorders

Answer 27

CD20