Anemia Flashcards
Define anemia
It’s a reduction of hemoglobin /hematocrit /or number of red blood cell of two standard deviation below the mean for. Age /sex/and race
What is erythropoiesis
It is the process of RBC production
Produced by growth hormone from the fetus
In fetal life erythropoietin is produced from ؟
Fetal liver during first and second
After birth production of erythropoietin shifts from liver to
The kidney
average life span of erythrocytes in adults and neonates
120 day in adults
60-90 day in neonate
Hemoglobin components
2 alpha
2 beta
Heme that contains iron
Special types of hemoglobin
Fetal hemoglobin (Hb F)
Adult hemoglobin (Hb A) (Hb A2)
What is the embryonic hemoglobin
Gower 1
Gower 2
Portland
The Gower hemoglobin in embryo is predominant till which week of gestation
6 weeks
The gower.hemoglobin is no longer detectable at ?
3 month of gestation
What type of hemoglobin has a higher affinity to oxygen
Fetal hemoglobin
Hb f starts to appear at which time of gestation
At 6 to 8 week of gestation
At term hemoglobin f percentage is
70 %
Between 6 to 12 month post term hemoglobin f percentage is
2%
At which gestational age hemoglobin A starts to appear
24 week of gestation