Anemia Flashcards

1
Q

Define anemia

A

It’s a reduction of hemoglobin /hematocrit /or number of red blood cell of two standard deviation below the mean for. Age /sex/and race

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2
Q

What is erythropoiesis

A

It is the process of RBC production
Produced by growth hormone from the fetus

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3
Q

In fetal life erythropoietin is produced from ؟

A

Fetal liver during first and second

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4
Q

After birth production of erythropoietin shifts from liver to

A

The kidney

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5
Q

average life span of erythrocytes in adults and neonates

A

120 day in adults
60-90 day in neonate

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6
Q

Hemoglobin components

A

2 alpha
2 beta
Heme that contains iron

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7
Q

Special types of hemoglobin

A

Fetal hemoglobin (Hb F)
Adult hemoglobin (Hb A) (Hb A2)

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8
Q

What is the embryonic hemoglobin

A

Gower 1
Gower 2
Portland

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9
Q

The Gower hemoglobin in embryo is predominant till which week of gestation

A

6 weeks

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10
Q

The gower.hemoglobin is no longer detectable at ?

A

3 month of gestation

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11
Q

What type of hemoglobin has a higher affinity to oxygen

A

Fetal hemoglobin

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12
Q

Hb f starts to appear at which time of gestation

A

At 6 to 8 week of gestation

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13
Q

At term hemoglobin f percentage is

A

70 %

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14
Q

Between 6 to 12 month post term hemoglobin f percentage is

A

2%

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15
Q

At which gestational age hemoglobin A starts to appear

A

24 week of gestation

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16
Q

At term the hemoglobin A percentage is

A

30%

17
Q

At age of 6 to 12 months the main hemoglobin in infants is

A

Hemoglobin A

18
Q

Normal ratio between hemoglobin A and hemoglobin A2 is

A

30:1

19
Q

What happened to the cardic output during anemia

A

It increases

20
Q

What happened to the blood circulation during anemia

A

Shunt to the vital organs

21
Q

What happened to the levels of erythropoietin during anemia

A

It increases

22
Q

The fractional volume of whole blood sample occupied by RBC is called

A

Hematocrit

23
Q

The concentration of RBC pigment in whole blood

A

Hemoglobin

24
Q

Volume of RBC in a blood sample

A

Mcv

25
Q

Variability of RBC size is called

A

RDW

26
Q

Gram of hemoglobin per 100 ml of blood

A

MCHC

27
Q

Mcv is

A

Size of RBC