ANS

Question 1

Motor - muscles of pharynx and larynx nucleus?

Answer 1

Dorsal Vagal nucleus and nucleus ambigus

Question 2

Sensory - skin of ext acoustic meatus and meninges

Answer 2

Solitary nucleus and Spinal trigeminal Nucleus

Question 3

Parasympathetic- viscera from neck to transverse colon

Answer 3

Dorsal Vagal nucleus and Nucleus ambigus

Question 4

Ach is released by

Answer 4

All preganglionic neurons

Question 5

NE is released by all postganglionic neurons except

Answer 5

Sweat glands (they use Ach)

Question 6

In gut, what neuropeptides are released

Answer 6

Somatostatin, neuropeptideY and ATP released with NE

Question 7

Alpha 1 receptors are found at

Answer 7

Post synaptic membranes of all ANS neuromuscular jxn (vasculature, bladder, GI tract, SA and AV nodes)

Question 8

Alpha 1 receptor triggers

Answer 8

Phospholipase C digestion of membrane phospholipids

Question 9

Digestion of membrane phospholipids produces

Answer 9

IP3 (activates Ca channels to increase Cytosolic Ca and activate Ca/CaMK) and DAG (activates PKC)

Question 10

PKC and Ca/Calmodulin Kinase cause

Answer 10

Protein phosphorylation

Question 11

Alpha 2 receptors are found at

Answer 11

Pre and post synaptic membranes of sympathetic nerves

Question 12

Alpha 2 receptors serve as

Answer 12

Regulatory mechanism for NE activation of alpha 1 receptors

Question 13

On post synaptic membranes alpha 2 receptors act

Answer 13

Antagonistically to suppress excitatory alpha 1 receptors

Question 14

On pre synaptic neuronal membrane alpha 2 monitor

Answer 14

Neurotransmitter levels in the synapse and contribute to negative feedback regulation of NE release

Question 15

Beta receptors are found in

Answer 15

Heart, bronchioles, adipose tissue and liver

Question 16

Beta receptors act by

Answer 16

G protein stimulation of adenylate Cyclase following binding of NE

Question 17

Adenylate cyclase increases cAMP which activates

Answer 17

cAMP dependent kinase PKA with resultant phosphorylation of targeted proteins

Question 18

Beta receptors 2 in heart are

Answer 18

Excitatory and produces positive chrono inotropic responses, lipolysis

Question 19

Beta 2 in smooth muscles produce

Answer 19

Inhibitory responses (dilation)

Question 20

Beta 3 produces

Answer 20

Lipolysis in adipose tissue

Question 21

Nicotinic antagonist

Answer 21

Curare/hexamethonium

Question 22

Muscarinic antagonist

Answer 22

Atropine

Question 23

In nicotinic receptor signalling, Ach released from

Answer 23

Pre-ganglionic neurons and bind to nicotinic receptors present on post ganglionic membranes

Question 24

In Muscarinic receptors signalling, Ach is released

Answer 24

From post ganglionic neurons and binds to Muscarinic receptors on parasympathetic neuroeffector jxn

Question 25

M2 and M3 receptors may

Answer 25

Activate or inhibit organ

Question 26

M1 is involved in

Answer 26

CNS transmission