Anti-bacterials Flashcards

1
Q

Binds PBP
bocks transpeptidase cross linking
AUTOLYTIC

A

Pencilinc G

V

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2
Q

hypersensitivity rxns
hemolytic anemia

Peniciliinase that cleaves B lactam ring

A

Penicillin G, V

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3
Q

Combine w/ clavulanic acid

Wider spectrum than penicillin HHELPS

A

AmOxicillin–greater Oral bioavailability
Ampicillin

H. influ
H. pylori
E. coli
L. monocytogenes
Proteus
Salmonella
Shigella
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4
Q

hypersensitivity rxns
rash
pseudomembranous colitis

penicillinase

A

Amoxicilin

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5
Q

Penicilinase resistant b/c of BULKY R group

used for S. Aureus (except MRSA)

A

Naffcillin–NAF used for STAPH
dicloxacillin
oxacillin

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6
Q

Used for PSEUDOMONAS and Gram - rods

A

Piperacillin, ticarcillin (AKA anti-pseudomonals)

…hypersensitivity rxn

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7
Q

B lactamase inhibitors?

added to protect AB from penicillinase (B lactamase, periplasmin, plasmid coded)

A

CAST

clavulanic
ACID
Sulbactam
Tazoactam

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