Anti Parasitic Drugs

Question 1

Albendazole

Answer 1

Albendazole is an FDA-approved medication for the treatment of a variety of parasitic worm infections. Albendazole is an antihelminthic medication with numerous indications such as cystic hydatid disease of the liver, lung, and peritoneum resulting from the larval form of the dog tapeworm, Echinococcus granulosus.

Question 2

Anti worm drugs

Answer 2

Albendazole
Metronidazole
Mebandazole
Vermicides (kill)
Vermifuge (expel)

Question 3

Five species of malaria

Answer 3

Ovale, malariae, vivax (deadly), falciparum (deadly), knowlosi

Question 4

Function of haem group

Answer 4

Converts hematin to hemazoin

Question 5

Proguanil

Answer 5

is a prophylactic antimalarial drug, which works by stopping the malaria parasite, Plasmodium falciparum and Plasmodium vivax, from reproducing once it is in the red blood cells. It does this by inhibiting the enzyme, dihydrofolate reductase, which is involved in the reproduction of the parasite.

Question 6

Primaquine

Answer 6

Prevents liver stage of parasite

Question 7

Tetracycline

Answer 7

No merozoite formation

Question 8

Which drugs stop erythrocytic schizogamy

Answer 8

Meflauine, artemisyene (stop erythrocytic schizogamy), chloroquine

Question 9

Artemistine

Answer 9

Not much effective
Blocks conversion of hematin to hemazoin

Question 10

Mechanism of primaquine and artemisnins

Answer 10

Damages cell membrane by ROS

Question 11

Mechanism of action of sulfadoxin pyrimethamine

Answer 11

Pteridine ___>PABA___>(DHPS)___> dihydropholate __ (DHPS)__> tetrahydrophorase___>(DHFR)__> thymidine