Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

From Flashcardlet > Anti-ulcer Drugs > Flashcards

Anti-ulcer Drugs Flashcards

1
Q

Where do peptic ulcers cause mucosal lining erosion?

A
  • esophageal
  • gastric
  • duodenal
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What do peptic ulcers cause hyper-secretion of?

A
  • HCl
  • Pepsin
  • pH of 2 to 5
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which bacteria is a predisposing factor to peptic ulcers?

A

Helicobacter pylori (H. pylori)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are predisposing factors to peptic ulcers?

A
  • Mechanical
  • Genetic
  • Environmental
  • Drugs
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the main symptom of peptic ulcers?

A

aching pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What foods should you avoid with peptic ulcers?

A
  • Hot, spicy,and greasy foods

- Alcohol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the recommendations when you take NSAIDS (including aspirin and oral glucocorticoids) to prevent peptic ulcers?

A

Take with food or in decreased dosages

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the nonpharmacological measures to treat peptic ulcers?

A
  • Avoid tobacco
  • Sit upright
  • Do not eat before bedtime
  • Wear loose clothes
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How does the tranquilizer Glycopyrrolate (Robinul) treat peptic ulcers?

A

Reduce vagal stimulation and decrease anxiety

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How does the anticholinergic Propantheline (Pro-Banthine) treat peptic ulcers?

A

Inhibits the release of HCl by blocking acetylcholine and histamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Why is the anticholinergic Propantheline (Pro-Banthine) given?

A

To take with meals to decrease acid secretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are most antacids made out of?

A
  • Aluminum
  • Magnesium
  • Calcium
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the action of an antacid?

A
  • Neutralize gastric acid

- Reduce pepsin activity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the systemic side effects of antacids?

A
  • Sodium excess
  • Water retention
  • Metabolic alkalosis
  • Acid rebound
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is a side effect of magnesium based antacids?

A

Diarrhea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is a side effect of aluminum based antacids?

A

Constipation

17
Q

What are four examples of histamine 2 blockers?

A
  • Tagamet
  • Zantac
  • Pepcid
  • Axid
18
Q

How do histamine 2 blockers work to treat ulcers?

A

Reduce gastric acid by blocking H2 receptors of parietal cells in stomach

19
Q

What are the side effects of histamine 2 blockers?

A
  • Headaches
  • Dizziness
  • Diarrhea
  • Constipation
  • Reversible impotence
  • Gynecomastia
20
Q

What are four examples of proton pump inhibitors?

A
  • Nexium
  • Prilosec
  • Protonix
  • Prevacid
21
Q

How do proton pump inhibitors treat peptic ulcers?

A

Reduce gastric acid by inhibiting hydrogen/potassium ATPase

22
Q

What are the common side effects of proton pump inhibitors?

A
  • Headache
  • Insomnia
  • Dizziness
  • Dry mouth
  • Flatulence
  • Abdominal pain
23
Q

What is an example of a pepsin inhibitor?

A

Carafate

24
Q

How do pepsin inhibitors treat peptic ulcers?

A

Combines with protein to form thick paste covering ulcer and protects from acid and pepsin

25
Q

What are the side effects of pepsin inhibitors?

A

Constipation

26
Q

What is an important nursing intervention when giving a pepsin inhibitor?

A

Give 30 minutes before meals and bedtime

27
Q

What is an example of a prostaglandin E1 analogue?

A

Cytotec

28
Q

How does a prostaglandin E1 analogue treat peptic ulcers?

A

Inhibits gastric acid secretion and protects mucosa

29
Q

What are the side effects of prostaglandin E1 analogues?

A
  • GI distress

- Constipation

30
Q

Which of the following are most likely to be included
in a dual drug therapy program for peptic ulcer
disease from H. pylori?

A

Omeprazole and clarithromycin

From Flashcardlet (107 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions