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FA Pharm > Antiarrhythmics > Flashcards

Antiarrhythmics Flashcards

1
Q

quinidine ADR

A

cinchonism (headache, tinnitus)

thrombocytopenia

TdP

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2
Q

procainamide ADR

A

reversible SLE-like syndrome (in slow acetylators)

thrombocytopenia

TdP

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3
Q

disopyramide ADR

A

heart failure

thrombocytopenia

TdP

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4
Q

lidocaine ADR

A

CNS stimulation/depression

cardiovascular depression

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5
Q

mexiletine ADR

A

DNS stimulation/depression

cardiovascular depression

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6
Q

flecainide ADR

A

proarrhythmic, especially post MI (CI)

CI in structural and ischemic heart disease

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7
Q

propafenone ADR

A

proarrythmic,e specially post MI (CI)

CI in structural and ischemic heart disease

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8
Q

beta blocker ADR

A

impotence

exacerbate COPD and asthma

heart: bradycardia, AV block, CHF

CNS: sedation, sleep alterations

may mask signs of hypoglycemia

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9
Q

metoprolol specific ADR

A

dyslipidemia

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10
Q

propranolol specific ADR

A

exacerbate vasospasm in Prinzmetal angina

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11
Q

sotalol ADR

A

TdP

excessive beta blockade

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12
Q

ibutilide ADR

A

TdP

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13
Q

amiodarone ADR

A

pulmonary fibrosis

hepatotoxicity

hypothyroidism/hyperthyroidism (amiodarone is 40% iodine by weight)

corneal deposits

skin deposits (blue/gray) resulting in photo dermatitis

neurologic effects

constipation

heart: bradycardia, heart block, CHF, low risk of TdP

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14
Q

verapamil ADR

A

constipation

flushing

edema

heart: CHF, AV block, sinus node depression

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15
Q

diltiazem ADR

A

constipation

flushing

edema

heart: CHF, AV block, sinus node depression

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16
Q

adenosine ADR

A

flushing

hypotension

chest pain

FA Pharm (3 decks)

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