Antiarrythmic

Question 1

Lidocaine

Answer 1

Class 1B
little effect on normal myocardium
fast

Question 2

Phenytoin

Answer 2

class 1B

Question 3

Mexiletine

Answer 3

Class 1B

Question 4

Flecainide

Answer 4

Class 1C
effects normal+damaged myocardium
non-selective

Question 5

Propafenone

Answer 5

Class 1C

Question 6

Quinidine

Answer 6

Class 1A
moderate blocker
blocks K efflux

Question 7

Procainamide

Answer 7

Class 1A

Question 8

Disopyramide

Answer 8

Class 1A

Question 9

Atenolol

Answer 9

Class II
selective

Question 10

Metaprolol

Answer 10

Class II
selective

Question 11

Bisoprolol

Answer 11

Class II
selective

Question 12

Propranolol

Answer 12

Class II
non-selective

Question 13

Amiodarone

Answer 13

Class III

Question 14

Dronedarone

Answer 14

Class III

Question 15

Vernakalant

Answer 15

Class III

Question 16

Verapamil

Answer 16

Class IV

Question 17

Diltiazem

Answer 17

Class IV

Question 18

Class system name

Answer 18

Vaughan Williams Classification

Question 19

what do antiarrhythmic agents do?

Answer 19

supress abnormal cardiac electrical activity

Question 20

Class I

Answer 20

Na channel blockers

Question 21

Are class I fast or slow response?

Answer 21

fast

Question 22

Class I: non-nodal or nodal?

Answer 22

Non-nodal

Question 23

how do Class I work?

Answer 23

depress phase 0, extend A.P duration and refractory period, supress excitability, decrease abnormal and triggered

Question 24

What does Class IA additionally block

Answer 24

K channels (extends A.P, delays phase 3)

Question 25

Class II

Answer 25

beta-adrenoreceptor blocker

Question 26

What hormones do Class II block

Answer 26

Catecholamine

Question 27

Class III

Answer 27

K channel blocker

Question 28

How do class III work?

Answer 28

delay phase 3 (extend 2)

Question 29

Class IV

Answer 29

Calcium entry blocker

Question 30

What channels do Class IV block?

Answer 30

L-type Ca channels

Question 31

How do Class IV work?

Answer 31

depress phase 0 (nodal), shorten phase 2 (non-nodal). decrease excitability, SAN rate, HR

Question 32

Class IV A.P+R.P-nodal

Answer 32

increase

Question 33

Class IV A.P+R.P-non-nodal

Answer 33

decrease

Question 34

Class III A.P+R.P

Answer 34

increase

Question 35

Class II A.P+R.P

Answer 35

increase

Question 36

Class I A.P+R.P

Answer 36

increase