Antibiotic Classification Flashcards
Name 6 antibiotic classes
Penicillins Cephalosporins Aminoglycosides Macrolides Fluoroquinolones Carbapenems
What is the general coverage for penicillins?
most Streptococcus
some N. meningitidis
many oral anaerobes except B. fragilis
List 5 common penicillins and their general uses
Penicillin G / Penicillin V Ampicillin /amoxicillin (+enterococcus) benzathine pen G (syphillis) piperacillin / piperacillin-tazobactam (+enterococcus, pseudomonas, GN coverage) cloxacillin (+MSSA)
Name a 1st generation cephalosporin (PO/IV) and their coverage
cephalexin/cefazolin (ancef)
mostly GP, some GN
Name a 2nd generation cephalosporin (PO/IV) and their coverage
cefuroxime/cefuroxime, cefoxitin, cefotetan
some GP and some GN
Name a 3rd generation cephalosporin (PO/IV) and their coverage
cefixime/cefotaxime, ceftriaxone (good streptococcal coverage, mostly GN), ceftazidime (no GP, mostly GN, Pseudomonas)
Name a 4th generation cephalosporin (PO/IV) and their coverage
- / cefepime (most GP, most GN, pseudomonas)
List 3 common aminoglycosides and their general uses
gentamycin tobramycin (+pseudomonas) amikacin (+pseudomonas)
What is the general coverage for aminoglycosides?
GN aerobic bacilli
What is the general coverage for macrolides?
GP, hemophilus, legionella, atypicals
List 3 common macrolides
erythromycin
clarithromycin
azithromycin
Name 3 common non-respiratory fluoroquinolones
ciprofloxacin (+pseudomonas)
ofloxacin
norfloxacin (for UTI only)
Name two respiratory fluoroquinolones
levofloxacin
moxifloxacin (+ anaerobes)
What is the general coverage for respiratory fluoroquinolones?
some GP, GN, atypical, legionella, mycoplasma, chlamydophila
Name 3 common carbapenems
imipenem (+pseudomonas)
meropenem (+pseudomonas)
ertapenem