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ABSITE > Antibiotics > Flashcards

Antibiotics Flashcards

1
Q

Cell wall synthesis abx

A

PCN, cephalosporins, carbopenems, vancomycin

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2
Q

30s ribosomal inhibitors

A

Tetracycline, amino glycosides, linezolid

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3
Q

50s ribosomal inhibitors

A

Erythromycin, clindamycin, cinercid

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4
Q

Inhibitors of DNA helicase

A

Quinolones

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5
Q

Produces oxygen radicals that break up DNA

A

Flagyl

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6
Q

How does PCN get resistances?

A

Plasmid transfer

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7
Q

How does MRSA get its resistance?

A

Mutation of cell wall binding protein

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8
Q

If your Peak is too high

A

Decrease the amount

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9
Q

If your trough is too high

A

Decrease frequency

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10
Q

What is a side effect of a third generation cephalosporin?

A

Cholestasis

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11
Q

What are the aminoglycosides?

A

Gentamicin and Tobramycin

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12
Q

What are the side effects of aminoglycosides?

A

Nephrotoxicity and ototoxicity

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13
Q

How does erythromycin work?

A

Works on motilin

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14
Q

What transplant med is a calcinurin inhibitor

A

Tacrolimus

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15
Q

What transplant med is a purine anti-metabolite

A

Mycofenilate mofitil

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16
Q

How do steroids work?

A

Prevent NFKB

17
Q

What are the side effects of amphotericine B?

A

Hypomag, hypokalemia, leukopenia, vfib, thrombocytopenia

18
Q

Side effect of silver sulfadiazine

A

Neutropenia

19
Q

Side effect of mafenide acetate

A

Metabolic acidosis
MA=MA

20
Q

Side effect of silver nitrate

A

HypoNa, hypoCl, hypoCa, hypoK

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