Antibiotics Flashcards
1
Q
IV Only ABX (5)
A
Penicillin G Pip/Taz Ceftriaxone Vancomycin Aminoglycosides
2
Q
Placenta Crossing ABX?
A
Cephalosporins Fluoroquinolones Sulfonamides (Kernicterus) Macrolides Tetracyclines Metronidazole
3
Q
Bactericidal ABX
A
Penicillins Cephalosporines Carbapenems Vancomycin Aminoglycosides Fluroquinolones Sulfa+TMP Nitrofurantoin
4
Q
Bacteriostatic ABX
A
Macrolides
Tetracyclines
Clindamycin
5
Q
Accumulates in bone
A
Clindamycin
6
Q
Causes C-Diff
A
Clindamycin
7
Q
Penicillin
A
Best w/ actively growing bacteria Poor tissue entry unless inflamed Enters CNS PenG is IV; PenV is PO PenG is more potent than PenV
8
Q
Vancomycin Side Effects
A
Redman Syndrome, Ototoxicity, Nephrotoxicity
9
Q
Penicillin AdvRxn
A
Hypersensitivity
10
Q
CNS Penetrating ABX (4)
A
Penicillin
Ceftriaxone (3rd Cephs)
Carbapenems
Sulfonamides
11
Q
Elongation Inhibitors
A
Macrolides (50s)
Clindamycin (50s)
12
Q
Initiation Inhibitors
A
Aminoglycosides (30s)
Tetracyclines (30s)
13
Q
DQ CRIMES
A
Doxycyclin Quinolone (cipro): CYP450 inhibitor Clindamycin Rifampin: (CYP450 inducer) Isoniazid: (hepatotoxic) Metronidazole: (ETOH) Erythromycin: (CYP450 Inhibition) Sulfonamides
14
Q
Macrolide Dosing Frequency
A
Erythromycin
15
Q
Macrolide Effectiveness
A
Erythromycin
