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Pharmacology > Antibiotics > Flashcards

Antibiotics Flashcards

1
Q

2 groups of antibiotics that work by inhibiting cell wall synthesis.

A

Beta lactams and glycopeptides

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2
Q

name 3 types of beta lactam.

A

penicillins
cephalosporins
carbapenems

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3
Q

Name 3 types of penicillin.

A

Benzylpenicillin
Flucloxacillin
Ampicillin/Amoxicillin

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4
Q

Give the uses of cephalosporins.

A

Staph. Aureus, step infections, Nisseriae, Haemophilus, coliforms.

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5
Q

Give the uses of carbapenems.

A

Enterobacteriae and anaerobic bacteria.

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6
Q

Give an example of a glycopeptide antibiotic

A

Vancomycin

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7
Q

Give the uses of benzylpenicillin.

A

Strep infections, pneumococcal pneumonia, Meningococcal meningitis

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8
Q

Give the uses of flucloxacillin

A

Staph. Aureus, Strep. Pyongenes

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9
Q

Give the uses of amoxicillin/ampicillin

A

UTIs, RTIs, Listeria meningitis, Enterococci infections.

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10
Q

Give the uses of vancomycin.

A

Sever staph infections - MRSA/ C.

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11
Q

Contraindications for benzylpenicillin & Flucloxacillin

A

Penicillin hypersensitivity

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12
Q

Side effects of benzylpenicillin& flucloxacillin

A

Hypersensitivity reactions

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13
Q

Contraindications of amoxicillin/ampicillin

A

Penicillin hypersensitivity

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14
Q

Side effects of amoxicillin/ampicillin

A

Nausea & vomiting

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15
Q

Contraindications of cephalosporins

A

Cephalosporin hypersensitivity

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16
Q

Side effects of cephalosporins

A

Antibiotic associated colitis

17
Q

CIs of carbapenems

A

Breast feeding

18
Q

SEs of carbapenems

A

^ platelet count and neurotoxicity at very high doses.

19
Q

CIs of glycopeptides (vancomycin)

A

Renal impairments, history of deafness, pregnancy

20
Q

SEs of glycopeptides (vancomycin)

A

Nephrotoxicity, ototoxicity (damage to ear - otto has hearing problems), blood disorders - neutropenia

21
Q

Name antibiotic mechanisms that inhibit nucleic acid synthesis and names for each.

A

Inhibit folate synthesis - trimethroprim, sulfonamides
Inhibit DNA gyrase - fluoroquinoloes
Bind to RNA polymerase - rifamipicin
DNA strand breaks -Nitrodimazoles, Metronidazoles

22
Q

Give the uses of trimethroprim

A

UTI

Pharmacology (2 decks)

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