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CPR > Anticoagulant Drugs > Flashcards

Anticoagulant Drugs Flashcards

1
Q

ASA

A

Target: COX
Irreversible
Antidote: Platelets

MI, stroke, VTE

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2
Q

NSAIDs

A

Target: COX
Reversible
Antidote: Platelets/time

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3
Q

Dipyridamole

A

Target: Phosphodiesterase
Reversible
Antidote: Platelets/time

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4
Q

Clopidogrel, Prasugrel, Ticagrelor

A

Target: ADP receptor
Clopidogrel and Prasugrel = Irreversible
Ticagrelor = Reversible
Antidote: Platelets/time

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5
Q

Anti-GPIIb/IIIa

A

Target: Xa
Irreversible
Antidote: Platelets

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6
Q

UF Heparin

A

Target: II, Xa
Antidote: Protamine
Monitoring: aPTT

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7
Q

Dalteparin

A 
LMWH (different peak times)
Target: Xa
Antidote: Protamine
Good for DVT
Monitoring: Anti Xa

DVT, PE, CAD, Angioplasty/stenting procedures.

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8
Q

Danaproid

A

Heparan Sulfate
Target: IIa/Xa
Antidote: None

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9
Q

Coumadin

A 
Decreases Vit K Factors
Transiently hypercoagulable
Teratogenic
Antidote: PCC > FFP and Vit K
Monitoring: PT
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10
Q

Dabigatran

A 
NOAC.
Pro Drug.
Target: II
Antidote: aPCC
Monitoring: Thrombin time

A Fib, ortho surg prophylaxis, VTE.

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11
Q

Enoxaparin

A 
NOAC - LMWH (different peak times)
Target: Xa
Antidote: Protamine
Good for DVT
Monitoring: Anti Xa

DVT, PE, CAD, Angioplasty/stenting procedures.

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12
Q

Tinzaparin

A 
LMWH (different peak times)
Target: Xa
Antidote: Protamine
Good for DVT
Monitoring: Anti Xa

DVT, PE, CAD, Angioplasty/stenting procedures.

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13
Q

Fondaparinux

A 
NOAC - LMWH (different peak times)
Target: Xa
Antidote: Protamine
Good for DVT
Monitoring: Anti Xa

DVT, PE, CAD, Angioplasty/stenting procedures.

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14
Q

Rivaroxaban

A

NOAC.
Target: Xa
Antidote: PCC
Monitoring: PT, Anti Xa

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15
Q

Apixaban

A

NOAC.
Target: Xa
Antidote: PCC
Monitoring: Anti Xa

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16
Q

Edoxaban

A

NOAC.
Target: Xa
Antidote: PCC
Monitoring: Anti Xa

17
Q

Betrixaban

A

NOAC.

Target: Xa

18
Q

Plasminogen Activators

A

Target: Plasmin
Antidote: Tranexamic acid, Cryoprecipitate

Arterial thrombosis/embolism.

CPR (4 decks)

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