Antidiarrheals

Question 1

What drug class does Diphenoxylate (Lomotil) fall in?

Answer 1

Antidiarrheal

Question 2

what is the action of this diphenoxylate?

Answer 2

Slows peristalsis

Question 3

Why is a prescription needed for Diphenoxylate? (lomotil)

Answer 3

it is a schedule 5 controlled substance

Question 4

What are the adverse effects of Diphenoxylate?(Lomotil)

Answer 4

tachycardia, dizziness, headache, flushing, nausea and vomiting
CNS EFFECTS

Question 5

what are the contrainidicatons of Diphenoxylate?

Answer 5

Diarrhea that is caused by toxic materials (E.coli, shigella, and E. coli)
Can worsen diarrhea

Question 6

what is the mechanism of action of Loperamide (Imodium)?

Answer 6

decrease GI motility by effecting intestinal muscles

Question 7

what are the adverse effects of Loperamide (Imodium)

Answer 7

abdominal pin, constipation, drowsiness, fatigue, and N/V

Question 8

what is the black box warning of Loperamide (Imodium)

Answer 8

Torsades de pointes, cardiac arrest and death

Question 9

what are side effects of Bismuth salts (Pesto-bismol)?

Answer 9

Black tongue and Black stool (normal)

Question 10

Bismuth is a ______ so it has antisecratory and possible antiinflammatory effects?

Answer 10

salicylate

Question 11

what effects do Bismuth have?

Answer 11

antibacterial and antiviral