Antihistamines, Decongestants, Antitussives, and Expectorants Flashcards Preview

NCLEX > Antihistamines, Decongestants, Antitussives, and Expectorants > Flashcards

Flashcards in Antihistamines, Decongestants, Antitussives, and Expectorants Deck (28):
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Dextromethorphan (Robitussin)
(Functional Classification)

Antitussive, nonopioid

1

Dextromethorphan (Robitussin)
(Chemical Classification)

Levorphanol derivative

2

Dextromethorphan (Robitussin)
(Mechanism of Action)

Depresses cough center in medulla by direct effect

3

Dextromethorphan (Robitussin)
(Uses)

Nonproductive cough caused by colds or inhaled irritants

4

Dextromethorphan (Robitussin)
(Contraindications)

Hypersensitivity

5

Dextromethorphan (Robitussin)
(Side Effects)

CNS: Dizziness, sedation, confusion, ataxia, fatigue
GI: Nausea

6

Dextromethorphan (Robitussin)
(Nursing Considerations)

ASSESS:
-COUGH: type, frequency, character, including sputum

PERFORM/PROVIDE:
-Increased fluids to liquify secretions
-Humidification of patient's room

7

Diphenhydramine (Benadryl)
(Functional Classification)

Antihistamine (1st generation, nonselective)

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Diphenhydramine (Benadryl)
(Chemical Classification)

Ethanolamine derivative, H1-receptor antagonist

9

Diphenhydramine (Benadryl)
(Mechanism of Action)

Acts on blood vessels, GI, respiratory system by competing with histamine for H1-receptor site; decreases allergic response by blocking histamine

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Diphenhydramine (Benadryl)
(Uses)

Allergy symptoms, rhinitis, motion sickness, antiparkinsonism, nighttime sedation, infant colic, nonproductive cough, insomnia in children

11

Diphenhydramine (Benadryl)
(Contraindications)

Hypersensitivity to H1-receptor antagonist, acute asthma attack, lower respiratory tract disease, neonates

12

Diphenhydramine (Benadryl)
(Side Effects)

CNS: Dizziness, Drowsiness, poor coordination, fatigue, anxiety, euphoria, confusion, paresthesia, neuritis, SEIZURES
CV: hypotension, palpitations
EENT: blurred vision, dilated pupils, tinnitus, nasal stuffiness, dry nose, throat, mouth
GI: nausea, anorexia, diarrhea
GU: Retention, dysuria, frequency
HEMA: THROMBOCYTOPENIA, AGRANULOCYTOSIS, HEMOLYTIC ANEMIA
INTEG: photosensitivity
MISC: ANAPHYLAXIS
RESP: increased thick secretions, wheezing, chest tightness

13

Diphenhydramine (Benadryl)
(Nursing Considerations)

ASSESS:
-urinary retention, frequency, dysuria; product should be discontinued
-CBC during long-term therapy; blood dyscrasias may occur
-Respiratory status: rate, rhythm, increase in bronchial secretions, wheezing, chest tightness

14

Diphenhydramine (Benadryl)
(Overdose Treatment)

Administer diazepam, vasopressors, phenytoin IV

15

Guaifenesin (Mucinex)
(Functional Classification)

Expectorant

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Guaifenesin (Mucinex)
(Mechanism of Action)

Increases the volume and reduces the viscosity of secretions in the trachea and bronchi to facilitate secretion removal

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Guaifenesin (Mucinex)
(Uses)

Productive and nonproductive cough

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Guaifenesin (Mucinex)
(Contraindications)

Hypersensitivity; chronic, persistent cough

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Guaifenesin (Mucinex)
(Side Effects)

CNS: drowsiness, headache, dizziness
GI: nausea, anorexia, vomiting, diarrhea

20

Guaifenesin (Mucinex)
(Nursing Considerations)

ASSESS:
-COUGH: type, frequency, character, including sputum; fluids should be increased to 2L/day

PERFORM/PROVIDE:
-increased fluids, room humidification to liquefy secretions

21

Loratadine (Claritin)
(Functional Classification)

Antihistamine, 2nd generation

22

Loratadine (Claritin)
(Chemical Classification)

Selective histamine (H1)-receptor antagonist

23

Loratadine (Claritin)
(Mechanism of Action)

Binds to peripheral histamine receptors, thereby providing antihistamine action without sedation

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Loratadine (Claritin)
(Uses)

Seasonal rhinitis, chronic idiopathic urticaria for those >/=2yr

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Loratadine (Claritin)
(Contraindications)

Hypersensitivity, acute asthma attacks, lower respiratory tract disease

26

Loratadine (Claritin)
(Side Effects)

CNS: sedation (more common with increased doses), headache, fatigue, restlessness
CV: sinus tachycardia
RESP: wheezing

27

Loratadine (Claritin)
(Nursing Considerations)

ASSESS:
-ALLERGY: hives, rash, rhinitis; monitor respiratory status
-LFTs, serum creatinine/BUN

PERFORM/PROVIDE
-Storage in tight container at room temp
-Increased fluids to 2L/day to decrease secretions