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FIRST AID CHAPTERS > Antiprotozoan > Flashcards

Antiprotozoan Flashcards

1
Q

Pryimethamine

A

toxoplasmosis

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2
Q

suramin and melarsoprol

A

trypansoma brucei

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3
Q

nifurtimox

A

t. cruzi

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4
Q

sodium stibogluconate

A

leishmaniasis

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5
Q

Permethrin

A

BLCOKS Na channels> neurotoxicity

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6
Q

melathion

A

ACH inhibiotr

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7
Q

lindane

A

blocks GABA> neutotoxicity

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8
Q

used to treat scabies and lice

A

Permethrin
malathion
lindane

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9
Q

Blocks the detoxification of heme to hemozoin> heme accumulates and is toxic to plasmodia

A

Chloroquine

Resistance from membrane pump that decreass intracellular concentration

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10
Q

tx for p. falciparum

A

artemether/lumefantrine

atovaquonone/proguanil

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11
Q

life threatening malarai

A

qunidine

artesunate

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12
Q

causes retinopathy and pruritis
visual disturbances
GI upset
ECG changes

A

Chloroquine

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13
Q

cinchonism

fetal toxcitity

A

Quinine (also used for babesia infectin)

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14
Q

Pyrimethamine

A

inhibits DHFR

P. falciparum
t. gondi

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15
Q

Primaquine

A

metabolites act as oxicants and cause parasitic and host cell dmage and death

tx HEPATIC forms of p. vivax and ovale

HEMOLYTIC ANEMIA IN G6PD PTS
HEMOLYTIC ANEMIA IN FETUS

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16
Q

IVERMECTIN

A

ACTIVATES GABA> worm paralysis and death

17
Q

Mebendazole

A

inhbitis microtubule synthesis

18
Q

Pyrantel pamoate

A

activates parasitic NICOTINE receptors> PARALYSIS

19
Q

Praziquantel

A

increases Ca cell uptake> parasitic contraction/paralysis

20
Q

Niclosamide

A

inhibits worm production of ATP

FIRST AID CHAPTERS (17 decks)

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