Aristada

Question 1

Generic

Answer 1

Aripiprazole lauroxil

Question 2

Manufacturer

Answer 2

Alkermes

Question 3

Dosage

Answer 3

441mg
662mg
882mg
1064mg

Question 4

Supplied

Answer 4

Prefilled syringe kit
441mg has three needles
21G 25mm 1 inch
20G 38mm 1 1/2 inch
20G 50mm 2 inch
662mg and above have two needles
20G 38mm 1 1/2 inch
20G 50mm 2 inch

Question 5

Steady state

Answer 5

4 months from initial

Question 6

Indication

Answer 6

Schizophrenia

Question 7

Criteria prior/ oral dose?

Answer 7

Yes, establish tolerability with oral aripiprazole

Question 8

Loading dose?

Answer 8

Yes, one injection of Aristada Initio 675mg AND one 30mg oral or,
21 days oral

Question 9

How often?

Answer 9

441mg and 662mg administered monthly
882mg monthly or every 6 weeks
1064mg every two months

Question 10

Administration site

Answer 10

Deltoid or gluteal

Question 11

Adverse events

Answer 11

Akathisia

Question 12

Specific populations

Answer 12

Mary cause EPS/ withdrawal symptoms in neonates if exposed in third trimester

Question 13

Drug interactions

Answer 13

No dosage changes recommended if CYP450 modulator are added before two weeks
Make dose change if added after 2 weeks

Question 14

Storage

Answer 14

Room temperature 68-77F