Asthma

Question 1

Which Polymorphism inform the choice of prescribing salmeterol or montelukast as addition therapy ?

Answer 1

ADRB2 Arg16

Question 2

What drugs are metabolised by CYP2D6 ?

Answer 2

Venalfaxine, fluoxetine, paroextine , nortriptyline,

Question 3

What is first cysteinyl leukotrine ?

Answer 3

LTC4

Question 4

Novel gene as sociated with clinical response are?

Answer 4

Leukotriene receptor antagonists

Question 5

Is thought to influence responses to exogenous administered corticosteroids (inhalation ) through the regulation of endogenous levels of corticosteroids.

Answer 5

CRHR1

Corticotropin - releasing hormone receptor 1 gene

Question 6

Was associated with the greatest improvement?

Answer 6

The G allele (gly) gly 231glu

Question 7

Neurokinn 2 receptor

Neurokinn A induce ………
Nerkonin 2 improve…….

Answer 7

Neurokinn A induce bronchonstriction and inflammation

Nerkonin 2 improve……. Asthma control with corticosteroids

Question 8

Which drug is substrate to NR3C1 ?

Answer 8

Dexamethasone

Question 9

STIP 1

Answer 9

Stress induced phosphoprotein 1 gene

Question 10

STIP associated with

Answer 10

Variable FEV1 (forced expiratory volume) response with the inhales corticosteroids flunisolide