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STEP Immunology > AutoAbs > Flashcards

AutoAbs Flashcards

1
Q

Anti-ACh R

A

Myasethenia gravis

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2
Q

Anti-basement membrane

A

Goodpasture syndrome

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3
Q

Anticardiolipin, lupus anticoagulant

A

SLE, antiphospholipid syndrome

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4
Q

Anticentromere

A

Limited Scleroderma (CREST syndrome

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5
Q

Antidesmosome (anti-desmoglein)

A

Pemphigus vulgaris

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6
Q

Anti-dsDNA, anti-Smith

A

SLE (anti-dsDNA is LUPUS RENAL DISEASE)

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7
Q

Anti-glutamic acid decarboxylase (GAD-65)

A

T1DM

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8
Q

Anti-hemidesmosome

A

Bullous pemphigoid

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9
Q

Anti-histone

A

Drug-induced lupus

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10
Q

Anti-Jo-1, anti-SRP, anti-Mi-2

A

Polymyositis, dermatomyositis

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11
Q

Antimicrosomal, antithyroglobulin

A

Hashimoto’s thyroiditis

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12
Q

Antimitochondrial

A

Primary billiary cirrhosis

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13
Q

Antinuclear antibodies

A

SLE, nonspecific

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14
Q

Antiparietal cell

A

Pernicious anemia

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15
Q

Anti-Scl-70 (anti-DNA topoisomerase I

A

Diffuse Scleroderma

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16
Q

Anti-smooth muscle

A

Autoimmune hepatitis

17
Q

Anti-SSA (anti-Ro), anti-SSB (anti-La)

A

Sjogren syndrome

18
Q

Anti-TSH R

A

Graves disease

19
Q

Anti-UI RNP (ribonucleoprotein)

A

Mixed Connective Tissue Disorder

20
Q

IgA anti-enomysial, IgA anti-tissue transglutaminase

A

Celiac disease

21
Q

MPO-ANCA/p-ANCA

A

Microscopic polyangiitis, eosinophilic granulomatous with polyangiitis (Churg-Strauss)

22
Q

MPO-ANCA

A

Pauci-immune glomerulonephritis

23
Q

PR3-ANCA/c-ANCA

A

Wegener’s granulomatosis (granulomatosis with polyangiitis)

24
Q

Rheumatoid Factor (IgM that targets IgG Fc region) (less specific, more for screening), anti-CCP(more specific, confirm)

A

Rhematoid arthritis

25
Q

Primary vs. Secondary Amyloidosis

A

Primary is Ig LCs form AL fibrils

Secondary is chronic inflammatory disease increases SAA (an APR)

STEP Immunology (13 decks)

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