Autonomics

Question 1

Anticholinergic toxicity effects

Answer 1

Hot as a hare - inc body temp due to dec sweating
Dry as a bone - muscarinic receptor blockage on sweat glands
Red as a beer - cutaneous vasodilation to dissipate heat to compensate dec sweating
Blind as a bat - cyclopegia and mydriasis
Mad as a hatter - disorientation
Full as a flask - urinary retention

Question 2

Muscarinic antagonist.

Antidote for organophosphate poisoning.

Answer 2

Atropine

Question 3

Organophosphate poisoning effects

Answer 3

DUMBBELSS

Diarrhea
Urination
Miosis
Bronchospasm
Bradycardia
Emesis
Lacrimation
Sweating
Salivation

Question 4

Direct sympathomimetics with B2 > B1 effects

Answer 4

Albuterol, salmeterol, terbutaline

Question 5

B2 agonist used for acute asthma or COPD

Answer 5

Albuterol

Question 6

B2 agonist used for long-term asthma or COPD management

Answer 6

Salmeterol

Question 7

B2 agonist used for acute bronchospasm in asthma and tocolysis

Answer 7

Terbutaline

Question 8

Direct sympathomimetic with B2 > B2, a. Used for heart failure, cardiogenic shock and cardiac stress testing

Answer 8

Dobutamine

Question 9

Direct sympathomimetic with D1=D2 > B > a. Used for unstable bradycardia, HF and shock

Answer 9

Dopamine

Question 10

Effects of dopamine at lower doses

Answer 10

Inotropic and chronotropic effects due to B effects

Question 11

Effects of dopamine at high doses

Answer 11

vasoconstriction due to alpha effects

Question 12

Direct sympathomimetic with B > alpha action. Used for anaphylaxis, asthma, open-angle glaucoma

Answer 12

Epinephrine

Question 13

Effects of epinephrine at high doses

Answer 13

Alpha effects

Question 14

Direct sympathomimetic with D1 action. Promotes natriuresis. Can cause hypotension and tachycardia

Answer 14

Fenoldopam

Question 15

Direct sympathomimetic with B1=B2 action

Answer 15

Isoproterenol

Question 16

Direct sympathomimetic with a1 action

Answer 16

Midodrine

Question 17

Direct sympathomimetic with B3 action. Used for urinary urge incontinence and overactive bladder

Answer 17

Mirabegron

Question 18

Direct sympathomimetic with a1 > a2 > b1 action that is used for hypotension and septic shock

Answer 18

Norepinephrine

Question 19

Direct sympathomimetic with a1 > a2 action.

Answer 19

Phenylephrine

Question 20

Uses for Phenylephrine

Answer 20

Hypotension (vasoconstrictor)
Ocular procedures (mydriatic)
Rhinitis (decongestant)
Ischemic priaprism