Bain Electricity Flashcards

1
Q

Amplitude of brain waves are measured in what?

A

MicroVolts, or millionths of volts

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2
Q

How many neurons in human brain?

A

86 billion

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3
Q

How many non neuronal cells in human brain?

A

85 billion

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4
Q

Weight of brain

A

1.3-1.4kg (3 lbs)

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5
Q

What % of body weight is brain in humans

A

2%

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6
Q

Herculano-Houzel 2012 on # of non neuronal cells

A

There are actually as many non neuronal cells as there are neuronal cells

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7
Q

Metabolism cost of neurons

A

6kcal/day per billion neurons [ Herculano-Houzel S (2011 ]

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8
Q

Brain metabolism scales linearly with

A

The number of neurons

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9
Q

Body metabolism (I assume excluding brain ) scales how?

A

Sub linearly with body mass (exponent of 3/4). Apparently scales linearly with body surface area

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10
Q

Thin apical dendrite diameter

A

diameter, 2.0 +- 0.4 micrometer,

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11
Q

How many neurotransmitter molecules does a synaptic vesicles contain?

A

5000

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12
Q

How does a neuron “decide” which synapses will release neurotransmitter when a neuron spike occurs?

A

The synapse decides , not the neuron

https://www.quora.com/How-does-a-neuron-%E2%80%9Cdecide%E2%80%9D-which-synapses-will-release-neurotransmitter-when-a-neuron-spike-occurs

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13
Q

Computer transistor width as of 2022

A

2nm

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14
Q

Neocortex accounts for what percentage of the brains volume?

A

80%

———-

Dunbar references anatomical measurements from 1981 and writes “With a neocortical volume of 1006.5 cc and a total brain volume of 1251.8 cc (Stephan et al. 1981), the neocortex ratio for humans is CR = 4.1.” (p. 682

https://aiimpacts.org/rate-of-neuron-firing/

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15
Q

Estimated number of neocortical neurons?

A

20 billion
—————

https://aiimpacts.org/rate-of-neuron-firing/
———-

The average total number of synapses in the neocortex of five young male brains was 164 x 10(12) (CV = 0.17).” Tang et al, 2001

“Number of synapses in cortex = 0.15 quadrillion (Pakkenberg et al., 1997; 2003)” – Eric Chudler

“The human brain has a huge number of synapses. Each of the 10^11 (one hundred billion) neurons has on average 7,000 synaptic connections to other neurons. It has been estimated that the brain of a three-year-old child has about 10^15 synapses (1 quadrillion). This number declines with age, stabilizing by adulthood. Estimates vary for an adult, ranging from 10^14 to 5 x 10^14 synapses (100 to 500 trillion).” Wikipedia accessed April 13 ’15, citing Drachman, D (2005). “Do we have brain to spare?”. Neurology 64 (12): 2004–5. We have not accessed most of the Drachman paper, but it does at least say “Within the liter and a half of human brain, stereologic studies estimate that there are approximately 20 billion neocortical neurons, with an average of 7,000 synaptic connections each”. It seems improbable that the average number of synapses per neuron in the brain is the same as that in the neocortex, weakly suggesting the Wikipedia contributor made an error.

These figures suggest that the neocortex accounts for between a third and most of synapses.

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16
Q

Average number of synapses per neocortical neuron

A

7000
——-

The average total number of synapses in the neocortex of five young male brains was 164 x 10(12) (CV = 0.17).” Tang et al, 2001

“Number of synapses in cortex = 0.15 quadrillion (Pakkenberg et al., 1997; 2003)” – Eric Chudler

“The human brain has a huge number of synapses. Each of the 10^11 (one hundred billion) neurons has on average 7,000 synaptic connections to other neurons. It has been estimated that the brain of a three-year-old child has about 10^15 synapses (1 quadrillion). This number declines with age, stabilizing by adulthood. Estimates vary for an adult, ranging from 10^14 to 5 x 10^14 synapses (100 to 500 trillion).” Wikipedia accessed April 13 ’15, citing Drachman, D (2005). “Do we have brain to spare?”. Neurology 64 (12): 2004–5. We have not accessed most of the Drachman paper, but it does at least say “Within the liter and a half of human brain, stereologic studies estimate that there are approximately 20 billion neocortical neurons, with an average of 7,000 synaptic connections each”. It seems improbable that the average number of synapses per neuron in the brain is the same as that in the neocortex, weakly suggesting the Wikipedia contributor made an error.

These figures suggest that the neocortex accounts for between a third and most of synapses.

17
Q

The average cortical neuron fires how many times a second?

A

.16 . This is an estimate based on the energy budget of the brain