Basic Principles - Epithelium Flashcards
Define the term tissue
A tissue is an aggregation of cells organised to perform one or more specific functions
What are the 4 types of tissue
Nervous - fast communication, brain
Connective - support, dermis of skin
Muscle - movement
Epithelium - lining
What are the 2 types of epithelium?
Lining epithelium - endothelium lines cardiovascular system, mesothelium lines internal cavities
Glandular epithelium - classified as connective tissue
What are the 2 types of glandular epithelium?
Endocrine - secrete product into bloodstream and has no ducts
Exocrine - secrete product onto a surface via ducts
What are the 3 mechanisms of secretion in glandular epithelium?
Merocrine - secretion occurs via exocytosis, where the substance is released from the cell without significant loss of cellular material
Holocrine - whole cell ruptures during release of product (sebaceous glands)
Apocrine - secretion involves the loss of a portion of the cell cytoplasm along with the substance being secreted
What are the 4 types of lateral specialisations?
Tight junctions
Intermediate junctions
Desmosomes
Gap junctions
How do you classify lining epithelium?
Number of layers - simple or stratified
Shape of cells - cuboidal, squamous or columnar
Presence of surface specialisations - keratin, cilia
How do you classify exocrine glands?
Duct type;
* simple - unbranched ducts
* compound - branched ducts
Composition of secretion;
* serous glands - watery, enzyme-rich fluid
* mucous glands - Secrete a thick, viscous fluid rich in glycoproteins called mucins, which form mucus when hydrated
* mixed glands - both
Mode of secretion - apocrine, merocrine, holocrine
Structure;
* unicellular - Composed of single cells dispersed among other cell types
* multicellular - Consist of clusters of glandular cells that work together to produce and secrete substances.
What are the morphological features of lining epithelium?
All cells in epithelial sheet are continuous so no intracellular substance between cells
Epithelial cells are polarised - have different surface regions apical and basal which carry out different functions
Avascular
Epithelial cells lie on a basement membrane
Apical membranes face is a free surface