Basic Principles - Epithelium Flashcards

1
Q

Define the term tissue

A

A tissue is an aggregation of cells organised to perform one or more specific functions

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2
Q

What are the 4 types of tissue

A

Nervous - fast communication, brain
Connective - support, dermis of skin
Muscle - movement
Epithelium - lining

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3
Q

What are the 2 types of epithelium?

A

Lining epithelium - endothelium lines cardiovascular system, mesothelium lines internal cavities
Glandular epithelium - classified as connective tissue

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4
Q

What are the 2 types of glandular epithelium?

A

Endocrine - secrete product into bloodstream and has no ducts
Exocrine - secrete product onto a surface via ducts

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5
Q

What are the 3 mechanisms of secretion in glandular epithelium?

A

Merocrine - secretion occurs via exocytosis, where the substance is released from the cell without significant loss of cellular material
Holocrine - whole cell ruptures during release of product (sebaceous glands)
Apocrine - secretion involves the loss of a portion of the cell cytoplasm along with the substance being secreted

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6
Q

What are the 4 types of lateral specialisations?

A

Tight junctions
Intermediate junctions
Desmosomes
Gap junctions

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7
Q

How do you classify lining epithelium?

A

Number of layers - simple or stratified
Shape of cells - cuboidal, squamous or columnar
Presence of surface specialisations - keratin, cilia

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8
Q

How do you classify exocrine glands?

A

Duct type;
* simple - unbranched ducts
* compound - branched ducts
Composition of secretion;
* serous glands - watery, enzyme-rich fluid
* mucous glands - Secrete a thick, viscous fluid rich in glycoproteins called mucins, which form mucus when hydrated
* mixed glands - both
Mode of secretion - apocrine, merocrine, holocrine
Structure;
* unicellular - Composed of single cells dispersed among other cell types
* multicellular - Consist of clusters of glandular cells that work together to produce and secrete substances.

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9
Q

What are the morphological features of lining epithelium?

A

All cells in epithelial sheet are continuous so no intracellular substance between cells
Epithelial cells are polarised - have different surface regions apical and basal which carry out different functions
Avascular
Epithelial cells lie on a basement membrane
Apical membranes face is a free surface

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