Basic Principles of Pharmacology Flashcards
1
Q
Routes of administration that undergoes significant first pass effect
A
ORAL
2
Q
Partially bypass effect
A
RECTAL
3
Q
Completely bypass effect
A
IV,IM,SC,SL,Inhalational, Topical Transdermal
4
Q
Route of administration with FASTEST ABSORPTION
A
Inhalation
5
Q
Drugs that display ZERO ORDER ELIMINATION KINETICS
A
WHATPET
Warfarin Heparin Aspirin Tolbutamide Phenytoin Ethanol Theophylline
6
Q
Drugs that Display Tachyphylaxis
A
MEDical students Love to watch CNN in HD
Metoclopramide Ephedrine Dobutamine LSD Calcitonin Nitroglycerin Nicotine Hydralazine Desmopressin
7
Q
Phase I Reactions
A
HORD
Hydrolysis
Oxidation
Reduction
Deamination
8
Q
Cytochrome P450 Inducers
A
Ethel Booba takes Phen Phen and Refuses Greasy Carb Shakes
Ethanol (chronic ingestion) Barbiturates (EXCEPT secobarbital) Phenytoin Rifampicin Griseofulvin Carbamazepine St. John's wort/Smoking
9
Q
Cytochrome P450 Inhibitors
A
Inhibitors Stop Cyber Kids from Eating GRApefrut QV
Isoniazid Sulfonamides Cimetidine Ketoconazole Erythromycin Grapefruit Juice Ritonavir (on acute ingestion) Amiodarone Quinidine Valproic Acid
