Block 1 Lecture 9 -- Humoral and Cellular Immune Responses Flashcards
1
Q
What chemokines are expressed in the follicle?
A
CXCL13
2
Q
What chemokines are expressed in the T-cell zone?
A
CCL19, CCL21
3
Q
What chemokine receptor do B cells upregulate when activated?
A
CCR7 (binds CCL19, CCL21)
4
Q
What chemokine receptor do T cells upregulated when activated?
A
CXCR5
5
Q
If too much Th1 response…
A
proinflammatory conditions
- diabetes
- GVHD
- arteriosclerosis
6
Q
If too much Th2 response…
A
antinflammatory
- infection
- alergy
- autoimmunity
7
Q
Th1 is involved in what aspect of immunity?
A
cellular immunity
8
Q
Th2 is involved in what aspect of immunity?
A
humoral immunity
