blood Flashcards

1
Q

what is blood made up of

A

red and white blood cells, platelets, and plasma

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2
Q

what is blood

A

a type of connective tissue

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3
Q

two main broad functions of blood

A

maintains homeostasis

transports substances

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4
Q

how many liters of blood are in the average adult

A

5

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5
Q

what is hematocrit and what are the average levels in males and females

A

the percent of blood composed of red blood cells

males: 41%
females: 38%

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6
Q

how many hemoglobin molecules are part of a RBC

A

240-250 million

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7
Q

how many heme components are there to hold oxygen

A

4

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8
Q

what is the shape of a RBC and how does this help its funcion

A

its a biconcave shape and this helps it to transport gases

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9
Q

how are RBC formed while we are embryos/fetuses

A

formed in the liver, spleen, and yolk sac

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10
Q

how are RBC formed after birth

A

red marrow in bones

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11
Q

what is the life span of RBC

A

100-120 days

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12
Q

what is erythropoietin, whats it triggered by, and what is the function

A

Its a hormone that controls the rate of RBC formation through negative feedback

its triggered by testosterone

when oxygen levels gets low erythropoietin triggers to make more RBCs

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13
Q

Destruction of RBC’s

A

passing through capillaries
-this damages the cells over time

macrophages
-these engulf dead cells

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14
Q

what are the 5 types of white blood cells

A
neutrophils
eosinophils
basophils
monocytes
lymphocytes
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15
Q

what is another name for WBC

A

leukocytes

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16
Q

neutrophils

A
  • have cytoplasmic granules
  • multilobed nucleus
  • account for 54-62% of the WBCs
17
Q

eosinophils

A
  • uniform granules
  • stain red
  • bilobed nucleus
  • 1-3% of WBC
18
Q

basophils

A
  • irrugularly shaped granules
  • stain deep blue
  • less than 1% of WBC
19
Q

monocytes

A
  • largest WBC
  • agranule
  • kidney shaped nuclues
  • 3-9% of WBC
  • live for several weeks/months
20
Q

lymphocytes

A

-slightly larger than RBC
- large round nucleus
-agranule
25-33% of WBC
-can live for years

21
Q

function of WBC

A

protect against infections by attacking bacteria

phagocytize bacterial cells: monocytes take care of the large particles, neutrophils for the small

produce protein (antibodies) that destroy other foreign particles: lymphocytes

-moderate allergic reactions: eosinophils

22
Q

WBC count

A

in a cubic mL of blood 5,000-10,000

23
Q

differential white blood cell count

A

this test lists the percentages of the different types of leukocytes in the blood sample

this is useful because certain percentages may increase or decrease if a certain infection of disease is taking place

24
Q

function of blood platelets and the normal counts

A

repair damage in ruptured blood vessels

130,000-360,000

25
Q

function of blood plasma

A

transports nutrients, gases and vitamins
regulates fluid and electrolyte balance
maintains a favorable pH

26
Q

3 plasma proteins and their functions

A
  1. albumin: helps maintain osmotic pressure
  2. globulins: alpha, beta, gamma-antibodies
  3. fibrinogen: coagulation
27
Q

nutrients and gases transported by blood

A
oxygen and carbon dioxide
amino acids
monosaccarides
nucleotides
lipids
28
Q

plasma electrolytes

A

they are absorbed from the intestine or released as by products of cellular metabolism
-Na, K, Ca, Mg, Cl, bicarbonate, phosphate, sulfate

29
Q

what is hemostasis

A

stopping of bleeding

30
Q

what are the steps involved in hemostasis

A
  1. blood vessel spasm
    - triggers next 2 stages
  2. Platelets plug formation
    - platelets adhere to each other and to end of ruptured blood vessel, this is effective in small vessels
  3. Blood coagulation: larger vessels
    - tissue thomoplastin
    - produces prothrombin activator
    - converts fibrinogen into fibrin which is a net like structure
31
Q

Bloodgroups

A

Agglutination: clumping of RBCs following a transfusion reaction

  • antigens: proteins on the surface of RBC
  • antibodies: carried in the plasma
32
Q

ABO blood group

A

if you have type A blood: A antigen, B antibody

AB: A&B antigen, neither antibody

O: no antigen, A&B antibody

33
Q

RH blood group

A

this is the postive or negative associated with blood types

  • RH antigen is present on RBC
  • inherited