Blood Flashcards

1
Q

Granular leukocytes

A

Grainy looking nucleus. Includes neutrophils, eosinopjils, and basophils.

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2
Q

Erythrocyte function

A
  1. Transport of respiratory gases when combined with hemoglobin
  2. Maintain acid base balance
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3
Q

Polycythemia

A
  1. RBC disorder characterized by increase in RBCs
  2. Usually caused by cancerous bone marrow
  3. Signs- increased blood thickness, slow blood flow, frequent hemorrhages, hypertension, distension of blood vessels.
  4. Treated by blood removal or chemotherapy or radiation to suppress bone marrow
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4
Q

Basophils

A
  1. Dark nucleus
  2. Are involved in inflammatory reactions and migrate to site of injury
  3. Contain histamine and anticoagulant heparin
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5
Q

Neutrophils

A
  1. Segmented nucleus, like beads
  2. Phagocytes that ingest and destroy invaders
  3. High with infections, low with B12 deficiency
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6
Q

Eosinophils

A
  1. Kidney shaped nucleus
  2. Attack objects that have already been coated with antibodies
  3. Phagocytes that will attack parasites, involved in allergic reactions
  4. High with infection or inflammation, low with bone marrow issues
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7
Q

Monocytes

A
  1. Much larger than other WBCs
  2. Aggressive phagocytes that attack larger microorganisms and cancer cells
  3. Release chemicals to attract neutrophils and other monocytes
  4. High with autoimmune and blood disorders, low with infections or bone marrow disorders
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8
Q

Lymphocytes

A
  1. Large nucleus with thin layer of cytoplasm
  2. B cells secrete antibodies
  3. T cells attack organisms
  4. NK cells- immune surveillance
  5. High with infections or leukemia, low with viral infections such as AIDs
  6. Receive signals from phagocytes
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9
Q

Clotting process

A

Rough blood vessel lining causes damaged tissues to release clotting factors. Platelets become sticky and plug the injury, prothrombin is converted to thrombin and reacts with fibrin to form a clot.

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10
Q

Clotting Disorders

A
  1. Hemophilia- genetic disease, lack of proteins to form blood clots.
  2. Thrombocytopenia- decrease in platelets causes bleeding
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11
Q

Anemia

A
  1. Not enough RBCs or deficient hemoglobin
  2. Iron deficiency, sickle cell, hemorrhagic- caused by trauma, aplastic- chemicals destroy bone marrow
  3. Symptoms- fatigue, pallor, faintness, headache, high heart and respiratory rates.
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12
Q

Plasma

A

Liquid part of blood containing water, dissolved food, waste, hormones and proteins.

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13
Q

Serum

A

Plasma without clotting agents.

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14
Q

Acidosis

A

Neutral blood (Ph should be 7.35-7.45)

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15
Q

Leukocytosis

A

Total WBC numbers over 10000 mm^3 of blood.

Frequently found in bacterial infections, and sign of leukemia.

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16
Q

Differential WBC count

A

Measures proportions of each type of WBC in blood sample.

17
Q

Leukemia

A
  1. White blood cell related cancers
  2. Acute- rapid development of symptoms. Chronic- slow development.
  3. Common symptoms- bone pain, recurrent infections, leukocytosis, fever, fatigue
18
Q

Mononucleosis

A
  1. Virus spread in saliva
  2. Causes leukocytosis and production of large, atypical lymphocytes with abundant cytoplasm
  3. Symptoms- fever, severe fatigue, sore throat, rash, enlargement of lymph nodes and spleen
19
Q

Universal Donor

A

Type O- no surface antigens, type A and B antibodies

20
Q

Universal Recipient

A

Type AB- no antibodies, Type A and B antigens

21
Q

Agglutinins

A

Antibodies

22
Q

Agglutinogens

A

Antigens (surface proteins)

23
Q

Rh factor

A

Extra surface protein

24
Q

Prothrombin time

A

Time it takes blood to clot. Normal time 12.5

25
Q

Hematocrit

A

Measure of total volume of RBCs compared to whole blood sample.

26
Q

Erythrocyte Sedimentation Rate

A

Distance RBCs fall to the bottom of a glass tube over a certain amount of time.

27
Q

Homozygous

A

Identical alleles (genotypes).