C1 Main Stuff Flashcards

1
Q

Type of biopsy that works by removing only a portion of the lesion

A

Incisional biopsy

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2
Q

Type of biopsy That works by removing the entire lesion

A

Excisional biopsy

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3
Q

Type of biopsy that works by removing a small tissue sample

A

Oligo biopsy

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4
Q

Type of biopsy that works By removing a thin core of tissue

A

Core needle biopsy

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5
Q

Type of biopsy that works by scraping tissue

A

Curettings

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6
Q

Fixative agent used routinely in histo pathology

A

Formaldehyde (formaline)

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7
Q

A fixative agent used routinely in cytopathology, it causes tissue to shrink and brittleness

A

Alcohol (ethanol 95%)

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8
Q

A fixative agent used in electron microscopy- tissue needs to be thin due to poor penetration and the tissue loses its antigenicity

A

Glutaraldehyde

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9
Q

Fixative agent used for biopsy of the kidney bone marrow lymph nodes and testicles

A

Zenker’s fluid

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10
Q

The most common combination of dyes used histopathology histopathology

A

Hematoxylin and eosin

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11
Q

Basic and positively charged dye

A

Hematoxylin

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12
Q

Acidic and negatively charged dye

A

Eosin

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13
Q

Dye used to identify bacteria like H.pylori and spiochetes

A

Warthin starrry

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14
Q

Dye used to identify helicobacter pylori

A

Giemsa

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15
Q

Dye used to identify acid fast bacteria (mycobacterium)

A

Ziehl neelson

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16
Q

Dye used to identify fungi

A

Grocery (or gromori) mtheneamine silver

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17
Q

Dye used to identify neutral mucins, glycogen, basement membrane and fungi

A

Perodic acid schiff (PAS)

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18
Q

Dye used to identify acid mucins (eg in intestinal goblet cells)

A

Alcian blue

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19
Q

Dye used to identify collagen

A

Masson’s trichrome

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20
Q

Dye to identify reticulin network in liver and pituitary gland

A

Reticulin

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21
Q

Dye used to identify fat in unfixed tissue

A

Oil-red

22
Q

Dye used to identify amyloid under polarized light

A

Congo red

23
Q

Dye used commonly in cytopathology like in cervical smears

A

Papnicolaou

24
Q

Marker in epithelial cells

A

Cytokeratins

25
Q

Marker in cells of mesynchymal origin

A

Vimentin

26
Q

Marker in smooth muscle cells

A

SMA

27
Q

Marker in leukocytes

A

CD45(LCA)

28
Q

Marker in T lymphocytes

A

CD3

29
Q

Marker in B lymphocytes

A

CD20

30
Q

Marker in Macrophages

A

CD68

31
Q

Marker in plasma cells

A

CD138

32
Q

Marker in endothelial cells

A

CD31 and CD34

33
Q

Markers in Neuroendocrine cells

A

Synaptophysin, chromogranin and CD56

34
Q

Markers in melanocytes

A

HMB45 and Melan-A

35
Q

Marker of intestine

A

CDX2

36
Q

Marker in the thyroid gland and lungs

A

TTF-1

37
Q

Marker in female genitalia tract

A

ER and PR

38
Q

Marker in prostate

A

PSA

39
Q

Marker in glial cells

A

GFAP

40
Q

Marker in myoepithelial/basal cells of the breast and prostate

A

P63

41
Q

Marker in proliferating (mitotically active) cells

A

Ki-67

42
Q

Shape or cells in oligodendroglioma

A

Fried eggs

43
Q

Shape of nuclei in granulosa cell tumour

A

Coffee beans

44
Q

arrangement of cells in lobular breast carcinoma

A

Indian file

45
Q

architectural pattern in fibrosarcoma

A

herringbone

46
Q

stag horns

A

blood vessels in hemangiopericytoma

47
Q

(blood vessels in oligodendroglioma

A

chicken wire

48
Q

cells in gastric adenocarcinoma

A

signet rings

49
Q

cells in angiosarcoma

A

hobnails

50
Q

fence-like arrangement of cells e.g. in schwannoma

A

palisades

51
Q

(cells arranged around a central point e.g. in retinoblastoma or medulloblastoma)

A

rosettes